School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Lab Chip. 2011 Aug 7;11(15):2577-82. doi: 10.1039/c1lc20153k. Epub 2011 Jun 15.
We describe a microfluidic system that uses a magnetic field to sort paramagnetic beads by deflecting them in the direction normal to the flow. In the experiments we systematically study the dependence of the beads' deflection on bead size and susceptibility, magnet strength, fluid speed and viscosity, and device geometry. We also develop a design parameter that can aid in the design of microfluidic devices for immunomagnetic multi-target sorting.
我们描述了一种使用磁场通过使顺磁性珠向与流动方向垂直的方向偏转而对其进行分选的微流控系统。在实验中,我们系统地研究了珠的偏转角对珠的大小和磁化率、磁场强度、流体速度和粘度以及器件几何形状的依赖性。我们还开发了一个设计参数,可用于辅助免疫磁多目标分选的微流控器件的设计。