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Exposure to traumatic events among treatment-seeking, alcohol-dependent women and men without PTSD.寻求治疗的、患有酒精依赖症的女性和男性创伤后应激障碍患者的创伤性事件暴露情况。
J Trauma Stress. 2010 Oct;23(5):649-52. doi: 10.1002/jts.20563.
2
Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders.全国共病调查复制研究I中的童年逆境与成人精神障碍：与《精神疾病诊断与统计手册》第四版（DSM-IV）障碍首次发病的关联
Arch Gen Psychiatry. 2010 Feb;67(2):113-23. doi: 10.1001/archgenpsychiatry.2009.186.
3
Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders.不良童年经历作为物质依赖的风险因素：情绪和焦虑障碍的部分中介作用。
Addict Behav. 2010 Jan;35(1):7-13. doi: 10.1016/j.addbeh.2009.07.004. Epub 2009 Aug 8.
4
Substance use after residential treatment among individuals with co-occurring disorders: the role of anxiety/depressive symptoms and trauma exposure.共病障碍患者住院治疗后的物质使用：焦虑/抑郁症状和创伤暴露的作用。
Psychol Addict Behav. 2009 Jun;23(2):303-14. doi: 10.1037/a0015355.
5
Trauma and PTSD in patients with alcohol, drug, or dual dependence: a multi-center study.酒精、药物或双重依赖患者的创伤与创伤后应激障碍：一项多中心研究。
Alcohol Clin Exp Res. 2008 Mar;32(3):481-8. doi: 10.1111/j.1530-0277.2007.00591.x. Epub 2008 Jan 22.
6
Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men.童年创伤的严重程度可预测女性而非男性的可卡因复吸结果。
Drug Alcohol Depend. 2008 Jan 1;92(1-3):208-16. doi: 10.1016/j.drugalcdep.2007.08.006. Epub 2007 Sep 27.
7
Do trauma history and PTSD symptoms influence addiction relapse context?创伤史和创伤后应激障碍症状会影响成瘾复发的情况吗？
Drug Alcohol Depend. 2007 Sep 6;90(1):89-96. doi: 10.1016/j.drugalcdep.2007.03.002. Epub 2007 Apr 24.
8
Six-month treatment outcomes of cocaine-dependent patients with and without PTSD in a multisite national trial.在一项多地点全国性试验中，患有和未患有创伤后应激障碍（PTSD）的可卡因依赖患者的六个月治疗结果。
J Stud Alcohol Drugs. 2007 May;68(3):353-61. doi: 10.15288/jsad.2007.68.353.
9
Trauma history and relapse probability among patients seeking substance abuse treatment.寻求药物滥用治疗的患者的创伤史和复发概率。
J Subst Abuse Treat. 2004 Sep;27(2):161-7. doi: 10.1016/j.jsat.2004.06.006.
10
Physical and sexual abuse history and addiction treatment outcomes.
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性别差异在创伤史和症状预测酒精和药物使用复发中的作用。

Gender differences in trauma history and symptoms as predictors of relapse to alcohol and drug use.

机构信息

Tri-State Tobacco and Alcohol Research Center, Addiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Ohio, USA.

出版信息

Am J Addict. 2011 Jul-Aug;20(4):307-11. doi: 10.1111/j.1521-0391.2011.00141.x. Epub 2011 May 31.

DOI:10.1111/j.1521-0391.2011.00141.x
PMID:21679261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3126098/
Abstract

The objective of this study was to determine whether there are gender-specific associations between trauma exposure and alcohol or drug relapse in alcohol-dependent adults. Participants were 51 men (n = 24) and women (n = 27) with alcohol dependence, 22 (43.1%) of whom relapsed during study participation. Severity of childhood trauma; number of lifetime events evoking fear, helplessness, or horror; and current trauma symptoms all predicted relapse in women, but not in men. These findings highlight the importance of assessing trauma history and providing treatment of trauma-related symptoms for individuals with alcohol and drug dependence, and for women in particular.

摘要

这项研究的目的是确定创伤暴露与酒精依赖成年人的酒精或药物复吸之间是否存在性别特异性关联。参与者为 51 名男性（n=24）和女性（n=27），他们均患有酒精依赖，其中 22 名（43.1%）在研究期间复发。儿童期创伤严重程度；一生中引发恐惧、无助或恐惧的事件数量；以及当前的创伤症状均预测女性复发，但不预测男性复发。这些发现强调了评估创伤史和为有酒精和药物依赖的个体，特别是女性，提供与创伤相关症状的治疗的重要性。