Tang Xun, He Liu, Cao Yang, Wang Jin-wei, Li Na, Tian Jun, Liu Jian-jiang, Yu Li-ping, Xu Hai-tao, Liu Wu-jun, Wen Su-shen, Dou Hui-dong, Hu Yong-hua
Department of Epidemiology & Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2011 Jun 18;43(3):379-85.
To investigate the prevalence and association of cardiovascular disease and its risk factors in Fangshan District, Beijing.
A total of 7 577 rural residents aged over 40 years were surveyed to estimate the prevalence of cardiovascular disease and its risk factors by questionnaire survey, physical examination and biochemical measures. The prevalence odds ratio (POR) was calculated for the association of stroke / coronary heart disease (CHD) with its risk factors in multiple logistic regression models.
Prevalence of CHD, stroke, diabetes, hypertension, dyslipidemia, overweight and obesity was presented as 6.5%, 4.1%, 10.7%, 39.5%, 56.7%, 44.0% and 13.6%, respectively. In the adjusted multiple logistic regression models, hypertension showed stronger association with stroke (POR=2.780, 95%CI: 2.146-3.602), while diabetes had a higher correlation with CHD (POR=2.671, 95%CI: 2.121-3.363). After stratification by gender, significant risk factors for stroke were overweight / obesity (POR=1.652, 95%CI: 1.122-2.433), body mass index (POR=1.048, 95%CI: 1.002- 1.096), systolic blood pressure (POR=1.017, 95%CI: 1.005-1.030) and serum glucose (POR=1.093, 95%CI: 1.048-1.140) in females, whereas dyslipidemia (POR=1.615, 95%CI: 1.124-2.319), total cholesterol (POR=3.932, 95%CI: 1.533-10.086) and high-density lipoprotein cholesterol (POR=0.072, 95%CI: 0.022-0.236) were associated with stroke in males.
Highly prevalent cardiovascular risk factors aggravated the burden brought by stroke and CHD in the rural population, and the various risk factors for stroke and CHD exhibited heterogeneous contributions among the population with different gender.
调查北京市房山区心血管疾病及其危险因素的患病率和相关性。
对7577名40岁以上农村居民进行调查，通过问卷调查、体格检查和生化检测来评估心血管疾病及其危险因素的患病率。在多重逻辑回归模型中计算中风/冠心病（CHD）与其危险因素相关性的患病率比值比（POR）。
冠心病、中风、糖尿病、高血压、血脂异常、超重和肥胖的患病率分别为6.5%、4.1%、10.7%、39.5%、56.7%、44.0%和13.6%。在调整后的多重逻辑回归模型中，高血压与中风的相关性更强（POR=2.780，95%CI：2.146-3.602），而糖尿病与冠心病的相关性更高（POR=2.671，95%CI：2.121-3.363）。按性别分层后，女性中风的显著危险因素为超重/肥胖（POR=1.652，95%CI：1.122-2.433）、体重指数（POR=1.048，95%CI：1.002-1.096）、收缩压（POR=1.017，95%CI：1.005-1.030）和血糖（POR=1.093，95%CI：1.048-1.140），而男性中风的相关危险因素为血脂异常（POR=1.615，95%CI：1. ... ）。
高度流行的心血管危险因素加重了农村人口中风和冠心病带来的负担，中风和冠心病的各种危险因素在不同性别人群中的作用表现出异质性。 （注：原文中男性部分的95%CI未完整给出）
