Polak Wojciech G, Nemes Balazs A, Miyamoto Shungo, Peeters Paul M J G, de Jong Koert P, Porte Robert J, Slooff Maarten J H
Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Clin Transplant. 2006 Sep-Oct;20(5):609-16. doi: 10.1111/j.1399-0012.2006.00525.x.
No consensus exists regarding the optimal reconstruction of the cavo-caval anastomosis in piggyback orthotopic liver transplantation (PB-LT). The aim of this study was to analyze our experience with end-to-side (ES) cavo-cavostomy. Outcome parameters were patient and graft survival and surgical complications. During the period 1995-2002 146 full-size PB-LT in 137 adult patients were performed with ES cavo-cavostomy without the routine use of temporary portocaval shunt (TPCS). In 12 patients (8%) this technique was used for implantation of second or third grafts. Veno-venous bypass was not used in any case and TPCS was performed only in eight patients (6%). One-, three- and five-yr patient and graft survival were 84%, 79% and 75%, and 81%, 74% and 69%, respectively. The median number of intraoperative transfusion of packed red blood cells (RBC) was 2.0 (range 0-33) and 30% of the patients (n = 43) did not require any RBC transfusion. Surgical complications of various types were observed after 49 LT (34%) and none of the complications was specifically related to the technique of ES cavo-cavostomy. Our experience indicates that PB-LT with ES cavo-cavostomy is a safe procedure, can safely be performed without the routine use of a TPCS, has a very low risk of venous outflow obstruction and can also be used effectively during retransplantations.
在背驮式原位肝移植(PB-LT)中,关于腔静脉吻合的最佳重建方式尚无共识。本研究的目的是分析我们采用端侧(ES)腔静脉吻合术的经验。观察指标为患者和移植物的生存率以及手术并发症。在1995年至2002年期间,对137例成年患者进行了146例全尺寸PB-LT,采用ES腔静脉吻合术,未常规使用临时门腔分流术(TPCS)。12例患者(8%)采用该技术植入第二或第三个移植物。所有病例均未使用静脉-静脉转流,仅8例患者(6%)进行了TPCS。1年、3年和5年的患者及移植物生存率分别为84%、79%和75%,以及81%、74%和69%。术中输注浓缩红细胞(RBC)的中位数为2.0(范围0 - 33),30%的患者(n = 43)无需输注任何RBC。49例肝移植(34%)后观察到各种类型的手术并发症,且无一例并发症与ES腔静脉吻合术技术有特定关联。我们的经验表明,采用ES腔静脉吻合术的PB-LT是一种安全的手术方法,无需常规使用TPCS即可安全进行,静脉流出道梗阻风险极低,在再次移植时也能有效应用。