Department of Chemistry, Washington State University, Pullman, Washington 99164, United States.
Anal Chem. 2011 Aug 1;83(15):5965-71. doi: 10.1021/ac200945k. Epub 2011 Jul 8.
Ion mobility spectrometry (IMS) has become the most widely used technology for trace explosives detection. A key task in designing IMS systems is to balance the explosives detection performance with size, weight, cost, and safety of the instrument. Commercial instruments are, by and large, equipped with radioactive (63)Ni ionization sources which pose inherent problems for transportation, safety, and waste disposal regulation. An alternative to a radioactive source is a corona discharge ionization source, which offers the benefits of simplicity, stability, and sensitivity without the regulatory problems. An IMS system was designed and built based on modeling and simulation with the goal to achieve a lightweight modular design that offered high performance for the detection of trace explosives using a corona ionization source. Modeling and simulations were used to investigate design alternatives and optimize parameters. Simulated spectra were obtained for 2,4,6-trinitrotoluene (TNT) and cyclo-1,3,5-trimethylene-2,4,6-trinitramine (RDX) and showed good agreement with experimentally measured spectra using a corona ionization source. The reduced mobilities for TNT and RDX obtained with corona ionization were 1.53 and 1.46 cm(2)/(V s), respectively, and this agreed well with literature values.
离子迁移谱（IMS）已成为最广泛使用的痕量爆炸物检测技术。在设计 IMS 系统时，一个关键任务是在仪器的尺寸、重量、成本和安全性方面平衡爆炸物检测性能。商用仪器通常配备有放射性（63）Ni 电离源，这给运输、安全和废物处理法规带来了固有问题。放射性源的替代物是电晕放电电离源，它具有简单、稳定和灵敏的优点，而没有监管问题。本研究设计并构建了一个基于建模和模拟的 IMS 系统，旨在实现轻量级模块化设计，使用电晕电离源实现痕量爆炸物的高性能检测。建模和模拟用于研究设计方案并优化参数。使用电晕电离源获得了 2,4,6-三硝基甲苯（TNT）和环-1,3,5-三亚甲基-2,4,6-三硝胺（RDX）的模拟谱，并与使用电晕电离源测量的实验谱吻合良好。用电晕电离获得的 TNT 和 RDX 的迁移率分别为 1.53 和 1.46 cm2/（V s），与文献值吻合较好。
