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随机前瞻性试验比较了急诊就诊的肾功能正常的输尿管结石患者即刻与延迟行输尿管镜检查的效果。

Randomized prospective trial comparing immediate versus delayed ureteroscopy for patients with ureteral calculi and normal renal function who present to the emergency department.

机构信息

Department of Urology, Rivoli Hospital, Rivoli, Torino, Italy.

出版信息

J Endourol. 2011 Jul;25(7):1137-41. doi: 10.1089/end.2010.0554. Epub 2011 Jun 17.

DOI:10.1089/end.2010.0554
PMID:21682597
Abstract

PURPOSE

To compare the safety and efficacy of emergency vs scheduled ureteroscopy with a prospective study that included patients who presented to the emergency department (ED) with renal colic from ureteral stones.

PATIENTS AND METHODS

There were 271 consecutive patients who were enrolled in this prospective study. Patients were randomized to emergency ureteroscopy (group A) or delayed ureteroscopy (group B). All patients underwent helical unenhanced CT (HUCT). Stone-free status was defined as the complete absence of residual fragments at 1 week postoperatively, assessed with HUCT, with no need for ancillary interventions after ureteroscopy.

RESULTS

Group A included 139 assessable patients. The overall stone-free rate was 93%. Neither location nor size was a significant prognostic factor (P>0.05). Single-session ureteroscopy failed to clear nine ureteral stones. A Double-J stent was placed in 27/139 patients. Group B included 100 assessable patients. Patients in the control group were scheduled for ureteroscopy after their departure from the ED. The overall stone-free rate was 90%. Single-session ureteroscopy failed to clear 10 ureteral stones. A Double-J stent was placed in 80/100 patients. There were no statistical differences with regard to stone diameter and location, complications, and stone-free rate between group A and group B patients. The rate of Double-J stent positioning was significantly higher (P<0.05) in group B patients.

CONCLUSIONS

In our experience, emergency ureteroscopy showed equal efficacy and safety compared with the elective procedure. It has the main advantage of providing both immediate relief from pain and stone fragmentation.

摘要

目的

通过前瞻性研究比较急诊与择期输尿管镜检查的安全性和疗效,该研究纳入了因输尿管结石就诊于急诊科(ED)的肾绞痛患者。

患者与方法

共有 271 例连续患者纳入本前瞻性研究。患者被随机分为急诊输尿管镜检查组(A 组)或延迟输尿管镜检查组(B 组)。所有患者均接受螺旋 CT 平扫(HUCT)。结石清除定义为术后 1 周 HUCT 检查无残留结石碎片,无需输尿管镜检查后辅助干预。

结果

A 组包括 139 例可评估患者。总体结石清除率为 93%。结石位置和大小均不是显著的预后因素(P>0.05)。单次输尿管镜检查未能清除 9 个输尿管结石。27/139 例患者留置双 J 支架。B 组包括 100 例可评估患者。对照组患者在离开 ED 后接受输尿管镜检查。总体结石清除率为 90%。单次输尿管镜检查未能清除 10 个输尿管结石。80/100 例患者留置双 J 支架。A 组和 B 组患者在结石直径和位置、并发症和结石清除率方面无统计学差异。B 组患者留置双 J 支架的比例明显更高(P<0.05)。

结论

根据我们的经验,与择期手术相比,急诊输尿管镜检查具有同等的疗效和安全性。它的主要优点是能立即缓解疼痛和碎石。

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