Kazemi Reza, Javid Amir, Ghandehari Amir Hossein, Salehi Hanieh
Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2024 Jul 11;29:27. doi: 10.4103/jrms.jrms_43_23. eCollection 2024.
The aim of this study was to compare the outcomes, success rate, and complications of performing elective ureteroscopy at different times: <1 week from renal colic initiation (early) and more than 1 week from renal colic initiation (late) in patients with ureteral stone larger than 6 mm.
This comparative observational study was conducted on 338 consecutive patients. Patients were evaluated in two groups: patients who underwent ureteroscopy in <1 week (A) and patients who underwent ureteroscopy in more than 1 week (B) from renal colic initiation. Helical unenhanced computed tomography was used to assess the size, location, and hardness of stone for all patients. Operation success was defined as complete clearance of stone with no stone residue (stone free) at 2-week postoperative ultrasonography with no need to further interventions. Operation data were collected using medical records, and postoperative complications were investigated at 2 weeks postoperative follow-up visits.
Group A included 165 patients and Group B included 173 patients. The overall mean stone size was 8.60 ± 1.12 mm: for Group A 9.13 ± 0.94 mm and for Group B 8.10 ± 1.04 mm ( < 0.001). Stone residues were found in 11 patients: 9 in Group A (5.4%) and 2 in Group B (1.1%) ( = 0.026). Nine patients needed repeated ureteroscopy: 8 (4.8%) in Group A and 1 (0.6%) in Group B ( = 0.015). A double-J stent was used for 85 (51.5%) patients in Group A and 66 (38.2%) patients in Group B ( = 0.016). Major intraoperative complications did not happen in any patients. Fifty-three (32.1%) patients in Group A and 28 (16.2%) patients in Group B suffered from postoperative complications ( = 0.001).
Our study revealed that performing elective ureteroscopy with an interval of more than 1 week from the onset of renal colic in combination with medical treatments was associated with less need for double-J stent placement, less need for repeated ureteroscopy, and fewer postoperative complications compared to performing elective ureteroscopy in <1 week from the renal colic onset in nonemergent patients with ureteral stone larger than 6 mm. Although the rate of ureteroscopy failure was higher among the patients who underwent ureteroscopy in <1 week from their renal colic initiation, there was no statistically significant relationship between performing ureteroscopy in <1 week and an increased risk for ureteroscopy failure.
本研究旨在比较不同时间进行选择性输尿管镜检查的结果、成功率及并发症:在输尿管结石大于6mm的患者中,肾绞痛发作后<1周(早期)和肾绞痛发作后超过1周(晚期)。
本比较性观察研究纳入了338例连续患者。患者分为两组进行评估:肾绞痛发作后<1周接受输尿管镜检查的患者(A组)和肾绞痛发作后超过1周接受输尿管镜检查的患者(B组)。所有患者均采用螺旋非增强计算机断层扫描评估结石的大小、位置和硬度。手术成功定义为术后2周超声检查结石完全清除且无结石残留(结石清除),无需进一步干预。通过病历收集手术数据,并在术后2周随访时调查术后并发症。
A组165例患者,B组173例患者。结石总体平均大小为8.60±1.12mm:A组为9.13±0.94mm,B组为8.10±1.04mm(<0.001)。11例患者发现有结石残留:A组9例(5.4%),B组2例(1.1%)(P = 0.026)。9例患者需要重复输尿管镜检查:A组8例(4.8%),B组1例(0.6%)(P = 0.015)。A组85例(51.5%)患者和B组66例(38.2%)患者使用了双J支架(P = 0.016)。所有患者均未发生重大术中并发症。A组53例(32.1%)患者和B组28例(16.2%)患者出现术后并发症(P = 0.001)。
我们的研究表明,对于输尿管结石大于6mm的非急诊患者,与肾绞痛发作后<1周进行选择性输尿管镜检查相比,肾绞痛发作后超过1周结合药物治疗进行选择性输尿管镜检查,双J支架置入需求更少,重复输尿管镜检查需求更少,术后并发症更少。尽管肾绞痛发作后<1周接受输尿管镜检查的患者中输尿管镜检查失败率较高,但肾绞痛发作后<1周进行输尿管镜检查与输尿管镜检查失败风险增加之间无统计学显著关系。