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食管穿孔的治疗:单中心经验

Esophageal perforation management: a single-center experience.

作者信息

Çarkıt Sedat, İpekten Funda, Karaağaç Mustafa, Gök Mustafa, Akyuz Muhammet

机构信息

Department of General Surgery, Erciyes University Faculty of Medicine, Kayseri-Türkiye.

Department of Biostatistics, Adıyaman University Faculty of Medicine, Adiyaman-Türkiye.

出版信息

Ulus Travma Acil Cerrahi Derg. 2024 Jan;30(12):875-882. doi: 10.14744/tjtes.2024.26020.

DOI:10.14744/tjtes.2024.26020
PMID:39668535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11849878/
Abstract

BACKGROUND

Esophageal perforation is a serious medical condition where a hole or tear develops in the esophagus, the muscular tube that connects the throat to the stomach. Although rare, the condition is potentially life-threatening, as it can lead to infection and inflammation in surrounding tissues, including the mediastinum, pleura, and peritoneum.

METHODS

Between 2014 and 2022, a retrospective study was conducted on cases of esophageal rupture treated at our institution. Eighteen cases were included in the study. Patient data, including age, gender, risk factors, delay in diagnosis, diagnostic method, site of perforation, etiology of perforation, treatment approach, complications, length of hospital stay, and outcomes, were collected. The Pittsburgh Severity Score (PSS) was calculated for each patient.

RESULTS

The mean patient age was 46.33 years, with a male predominance (72.2%). Causes included iatrogenic (22.2%), foreign body (50%), and trauma (27.8%). Perforations primarily occurred in the cervical (38.9%), thoracic (33.3%), and distal esophagus (27.8%). Higher mortality was associated with elevated white blood cell count (WBC), delayed diagnosis, and contrast leakage (p<0.05). Computed tomography (CT) findings and complications significantly influenced intensive care unit (ICU) stay, with abscesses reducing and mediastinitis increasing the duration (p<0.05). Other factors, including age, length of hospitalization, gender, etiology, and treatment type, did not significantly affect Pittsburg Severity Scores (p>0.05).

CONCLUSION

Esophageal perforation remains a challenging clinical condition associated with significant morbidity and mortality. To optimize patient outcomes, rapid diagnosis, risk stratification using tools such as the PSS, and tailored management strategies are essential.

摘要

背景

食管穿孔是一种严重的病症,即连接咽喉与胃部的肌性管道食管出现孔洞或撕裂。尽管这种情况罕见,但它可能危及生命,因为它会导致周围组织(包括纵隔、胸膜和腹膜)发生感染和炎症。

方法

2014年至2022年期间,对我院治疗的食管破裂病例进行了一项回顾性研究。该研究纳入了18例病例。收集了患者数据,包括年龄、性别、危险因素、诊断延迟、诊断方法、穿孔部位、穿孔病因、治疗方法、并发症、住院时间和结局。为每位患者计算匹兹堡严重程度评分(PSS)。

结果

患者平均年龄为46.33岁,男性占主导(72.2%)。病因包括医源性(22.2%)、异物(50%)和外伤(27.8%)。穿孔主要发生在颈部(38.9%)、胸部(33.3%)和食管远端(27.8%)。白细胞计数升高、诊断延迟和造影剂外漏与较高的死亡率相关(p<0.05)。计算机断层扫描(CT)结果和并发症对重症监护病房(ICU)住院时间有显著影响,脓肿会缩短住院时间,纵隔炎会延长住院时间(p<0.05)。其他因素,包括年龄、住院时间、性别、病因和治疗类型,对匹兹堡严重程度评分没有显著影响(p>0.05)。

结论

食管穿孔仍然是一种具有挑战性的临床病症,伴有显著的发病率和死亡率。为了优化患者结局,快速诊断、使用PSS等工具进行风险分层以及制定个性化的管理策略至关重要。

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本文引用的文献

1
Esophageal perforation etiology, outcome, and the role of surgical management - an 18-year experience of surgical cases in a referral center.食管穿孔的病因、转归和外科治疗的作用——18 年转诊中心外科治疗经验。
BMC Surg. 2023 Jun 27;23(1):177. doi: 10.1186/s12893-023-02080-w.
2
Esophageal stenting with minimally-invasive surgical intervention for delayed spontaneous esophageal perforation.采用微创外科干预进行食管支架置入术治疗延迟性自发性食管穿孔。
J Thorac Dis. 2023 Mar 31;15(3):1228-1235. doi: 10.21037/jtd-22-1316. Epub 2023 Mar 10.
3
Safety and Efficacy of Nonoperative Treatment in Esophageal Perforation Caused by Foreign Bodies.
异物导致食管穿孔的非手术治疗的安全性和疗效。
Clin Transl Gastroenterol. 2022 Jan 19;13(1):e00451. doi: 10.14309/ctg.0000000000000451.
4
Could the Pittsburgh Severity Score guide the treatment of esophageal perforation? Experience of a single referral center.匹兹堡严重度评分能否指导食管穿孔的治疗?单中心经验。
J Trauma Acute Care Surg. 2022 Jan 1;92(1):108-116. doi: 10.1097/TA.0000000000003417.
5
CT Esophagography for Evaluation of Esophageal Perforation.用于评估食管穿孔的CT食管造影术
Radiographics. 2021 Mar-Apr;41(2):447-461. doi: 10.1148/rg.2021200132. Epub 2021 Feb 12.
6
Minimally invasive management of esophageal perforation.食管穿孔的微创治疗
Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Jul 3;26(3):496-503. doi: 10.5606/tgkdc.dergisi.2018.15354. eCollection 2018 Jul.
7
Surgical management and prognostic factors in esophageal perforation caused by foreign body.异物所致食管穿孔的外科治疗及预后因素
Esophagus. 2019 Apr;16(2):188-193. doi: 10.1007/s10388-018-0652-6. Epub 2019 Feb 15.
8
Does the Pittsburgh Severity Score predict outcome in esophageal perforation?匹兹堡严重度评分能否预测食管穿孔的结局?
Dis Esophagus. 2019 Feb 1;32(2). doi: 10.1093/dote/doy109.
9
Spotlight on esophageal perforation: A multinational study using the Pittsburgh esophageal perforation severity scoring system.聚焦食管穿孔:使用匹兹堡食管穿孔严重程度评分系统的多国研究。
J Thorac Cardiovasc Surg. 2016 Apr;151(4):1002-9. doi: 10.1016/j.jtcvs.2015.11.055. Epub 2015 Dec 13.
10
Western Trauma Association Critical Decisions in Trauma: Diagnosis and management of esophageal injuries.西方创伤协会创伤关键决策:食管损伤的诊断与管理
J Trauma Acute Care Surg. 2015 Dec;79(6):1089-95. doi: 10.1097/TA.0000000000000772.