Laboratoire de Neurosciences fonctionnelles et Pathologie, CNRS-UMR 8160, Université Lille-Nord de France, Villeneuve d'Ascq, France.
Cortex. 2011 Oct;47(9):1107-15. doi: 10.1016/j.cortex.2011.05.007. Epub 2011 May 17.
The present study investigated emotional responses to music by using multidimensional scaling (MDS) analysis in patients with right or left medial temporal lobe (MTL) lesions and matched normal controls (NC). Participants were required to evaluate emotional dissimilarities of nine musical excerpts that were selected to express graduated changes along the valence and arousal dimensions. For this purpose, they rated dissimilarity between pairs of stimuli on an eight-point scale and the resulting matrices were submitted to an MDS analysis. The results showed that patients did not differ from NC participants in evaluating emotional feelings induced by the musical excerpts, suggesting that all participants were able to distinguish refined emotions. We concluded that the ability to detect and use emotional valence and arousal when making dissimilarity judgments was not strongly impaired by a right or left MTL lesion. This finding has important clinical implications and is discussed in light of current neuropsychological studies on emotion. It suggests that emotional responses to music can be at least partially preserved at a non-verbal level in patients with unilateral temporal lobe damage including the amygdala.
本研究通过多维标度分析（MDS），调查了右或左内侧颞叶（MTL）损伤患者和匹配的正常对照组（NC）对音乐的情绪反应。参与者需要评估九段音乐片段的情绪差异，这些片段是沿着效价和唤醒维度选择的，以表达逐渐变化。为此，他们在八点量表上对刺激对之间的差异进行评分，所得矩阵提交给 MDS 分析。结果表明，患者在评估音乐片段引起的情绪感受方面与 NC 参与者没有差异，这表明所有参与者都能够区分细微的情绪。我们得出结论，当进行差异判断时，检测和使用情绪效价和唤醒的能力不会因右或左 MTL 损伤而受到严重损害。这一发现具有重要的临床意义，并结合当前关于情绪的神经心理学研究进行了讨论。这表明，在包括杏仁核在内的单侧颞叶损伤患者中，音乐的情绪反应至少可以在非言语层面上得到部分保留。
