Department of Chemical Engineering, Nara National College of Technology, Yamato-koriyama, Nara, Japan.
Colloids Surf B Biointerfaces. 2011 Oct 15;87(2):510-3. doi: 10.1016/j.colsurfb.2011.05.049. Epub 2011 Jun 1.
Glucose oxidase (GOD) was encapsulated in vesicles containing a photoionizable Malachite Green leuconitrile derivative (MGL). Subsequent UV irradiation of MGL afforded the fusion of GOD- and glucose-encapsulating vesicles and thus decreased the concentration of glucose in the vesicles. The time dependence of the vesicle fusion was studied using fluorescent probe molecules. This phototriggered fusion could be instrumental in the development of a system for the production of nanometer-sized bioreactors.
葡萄糖氧化酶（GOD）被包裹在含有可光离子化孔雀绿亮腈衍生物（MGL）的囊泡中。随后对 MGL 进行紫外线照射，导致 GOD 和葡萄糖包封囊泡融合，从而降低了囊泡中葡萄糖的浓度。使用荧光探针分子研究了囊泡融合的时间依赖性。这种光触发融合可能有助于开发用于生产纳米级生物反应器的系统。
