Ghosh Arjun K, Hatfield Emma, Connolly Susan
Cardiovascular Medicine, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.12.2008.1349. Epub 2009 May 12.
This report presents an interesting case of acute myocardial stunning secondary to catecholamine surge from a phaeochromocytoma. A 39-year-old British Asian man was admitted with chest pain, labile blood pressure, dynamic ECG changes and positive troponin I level. Echocardiogram showed severe global impairment of his left ventricular systolic function but sparing of the basal segments. Portable renal ultrasonography revealed a 6 cm mass in the left adrenal gland. The clinical suspicion was of catecholamine-induced acute myocardial dysfunction secondary to underlying phaeochromocytoma. Intravenous alpha blockade resulted in a dramatic clinical improvement and near resolution of the echocardiographic abnormalities. Subsequent coronary angiography confirmed normal coronary arteries. He was discharged, well, on oral alpha-adrenergic and beta-adrenergic blockade. Outpatient metaiodobenzylguanidine scanning was consistent with the diagnosis and a left phaeochromocytoma was successfully removed laparoscopically.
本报告介绍了一例因嗜铬细胞瘤导致儿茶酚胺激增继发急性心肌顿抑的有趣病例。一名39岁的英国亚裔男性因胸痛、血压不稳定、动态心电图改变及肌钙蛋白I水平阳性入院。超声心动图显示其左心室收缩功能严重整体受损,但基底节段未受累。便携式肾脏超声检查发现左肾上腺有一个6厘米的肿块。临床怀疑是潜在嗜铬细胞瘤继发儿茶酚胺诱导的急性心肌功能障碍。静脉注射α受体阻滞剂使临床症状显著改善,超声心动图异常几乎消失。随后的冠状动脉造影证实冠状动脉正常。他出院时情况良好,口服α肾上腺素能和β肾上腺素能阻滞剂。门诊间碘苄胍扫描与诊断相符,成功通过腹腔镜切除了左侧嗜铬细胞瘤。