Tassinari Davide, Gallinella Giorgio, Salfi Nunzio C, Elleri Daniela, Forti Sara, Bonvicini Francesca, Bernardi Filippo
S.Orsola-Malpighi Hospital, University of Bologna, Department of Paediatrics, Via Massarenti 11, Bologna 40138, Italy.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.10.2008.1058. Epub 2009 Mar 17.
A 13-year-old girl with persistent fever, pharyngitis, acute anaemia, peripheral blood and bone marrow positive for parvovirus B19 DNA.Microscopic findings of gastrointestinal biopsy showed diffuse vacuolar alteration of the cytoplasma of duodenal enterocytes and virological analysis demonstrated the presence of parvovirus in lymphocytes of the duodenal wall's epithelial layer.In unexplained gastrointestinal pathologies, the role of parvovirus B19 infection should be investigated.
一名13岁女孩持续发热、患咽炎、急性贫血，细小病毒B19 DNA在其外周血和骨髓中呈阳性。胃肠道活检的显微镜检查结果显示十二指肠肠上皮细胞胞质弥漫性空泡改变，病毒学分析表明十二指肠壁上皮层淋巴细胞中存在细小病毒。在不明原因的胃肠道病变中，应研究细小病毒B19感染的作用。
