Onur Ozge Ozberk, Guneysel Ozlem, Saritemur Murat, Denizbasi Arzu
Marmara University, Emergency Medicine, Tophanelioglu c, Istanbul, 34150, Turkey.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0580. Epub 2009 Feb 26.
Spontaneous haemoperitoneum due to rupture of hepatocellular carcinoma (HCC) is a surgical emergency and may have catastrophic outcomes.
A 62-year-old male presented with nausea, dizziness and low back pain. There was no history of malignancy. Physical examination revealed a surgical abdominal emergency, but there was no physical finding that pointed towards a specific diagnosis. Laboratory studies revealed decreased haematocrit (27.6%) and increased INR (2.8) levels. A computed tomography scan showed a tumoral lesion within the fourth segment of the liver and fluid collection (haemoperitoneum) with normal vascular and intra-abdominal structures.
Exploratory laparotomy was performed; the appearance of the liver was cirrhotic and nodular. Actively bleeding tumoral lesion was confirmed in fourth segment of the liver, "packing" applied with sponges to stop bleeding. On the post-operative day 22, the patient was discharged.
Spontaneous rupture of HCC is rare and should be considered in the differential diagnosis of non-traumatic spontaneous haemoperitoneum.
肝细胞癌(HCC)破裂导致的自发性血腹是一种外科急症,可能会产生灾难性后果。
一名62岁男性出现恶心、头晕和腰痛。无恶性肿瘤病史。体格检查显示为外科腹部急症,但未发现指向特定诊断的体征。实验室检查显示血细胞比容降低(27.6%),国际标准化比值(INR)升高(2.8)。计算机断层扫描显示肝脏第四段有肿瘤病变及液体积聚(血腹),血管和腹内结构正常。
进行了剖腹探查术;肝脏外观呈结节状肝硬化。确认肝脏第四段有活动性出血的肿瘤病变,用海绵进行“填塞”以止血。术后第22天,患者出院。
HCC自发性破裂罕见,在非创伤性自发性血腹的鉴别诊断中应予以考虑。