Athanasopoulos Anastasios, Giannitsas Konstantinos
Urodynamic Urology Unit, Department of Urology, Medical School, University of Patras, 26500 Patra, Greece.
Adv Urol. 2011;2011:820816. doi: 10.1155/2011/820816. Epub 2011 Jun 7.
Overactive bladder is a common and bothersome condition. Antimuscarinic agents, as a class, are the cornerstone of medical treatment of overactive bladder. They offer significant improvements in symptoms and patients' quality of life. Antimuscarinics are generally well tolerated with mild and predictable side effects. Available antimuscarinics have small, yet statistically significant, differences in their efficacy and tolerability profiles. In clinical practice, finding the agent that offers the optimum balance of efficacy and side effects for an individual patient remains the major challenge.
膀胱过度活动症是一种常见且令人困扰的病症。抗毒蕈碱药物作为一类药物，是膀胱过度活动症药物治疗的基石。它们能显著改善症状和患者的生活质量。抗毒蕈碱药物一般耐受性良好，副作用轻微且可预测。现有的抗毒蕈碱药物在疗效和耐受性方面存在微小但具有统计学意义的差异。在临床实践中，为个体患者找到疗效和副作用达到最佳平衡的药物仍然是主要挑战。
