Klinik für Kinder-und Jugendmedizin, Universitätsklinikum der RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.
Gastroenterol Res Pract. 2011;2011:271404. doi: 10.1155/2011/271404. Epub 2011 May 24.
The aim of this paper was to investigate the temporal association of gastroesophageal reflux (GER) and body movement in infants. GER were registered by combined impedance-pH, documentation of body movement was done by video. Videorecording time (Vt) was divided into "resting time" and "movement time" and analyzed for occurrence of GER. Association was defined as movement 1 minute before/after the beginning of a GER. Statistical evaluation was by Fisher's exact test. In 15 infants, 341 GER were documented during Vt (86 hours). 336 GER (99%) were associated with movement, only 5 episodes (1%) occured during resting time. Movement was significantly associated with the occurrence of GER (P < .0001). There is a strong temporal association between GER and body movement in infants. However, a clear distinction between cause and effect could not be made with the chosen study design. Combined impedance-pH has proven to be the ideal technique for this approach.
本文旨在研究婴儿胃食管反流（GER）与身体运动之间的时间关联。采用阻抗-pH 联合监测 GER，通过视频记录身体运动。将录像时间（Vt）分为“休息时间”和“运动时间”，并分析 GER 的发生情况。关联定义为 GER 开始前/后 1 分钟的运动。统计评估采用 Fisher 精确检验。在 15 名婴儿中，Vt（86 小时）期间记录了 341 次 GER。336 次 GER（99%）与运动有关，仅 5 次（1%）发生在休息时间。运动与 GER 的发生有显著相关性（P <.0001）。婴儿的 GER 与身体运动之间存在很强的时间关联。然而，由于所选的研究设计，无法明确区分因果关系。阻抗-pH 联合监测已被证明是这种方法的理想技术。
