Department of Pediatric Gastroenterology, Center for Advanced Research in Neuromuscular Gastrointestinal Disorders, Nationwide Children's Hospital, Ohio State University, Columbus, OH, USA.
J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):129-39. doi: 10.1097/MPG.0b013e3181ffde67.
Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid reflux events. pH-MII technology is especially useful in the postprandial period or at other times when gastric contents are nonacidic.pH-MII was recently recognized by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition as being superior to pH monitoring alone for evaluation of the temporal relation between symptoms and gastroesophageal reflux. In children, pH-MII is useful to correlate symptoms with reflux (particularly nonacid reflux), to quantify reflux during tube feedings and the postprandial period, and to assess efficacy of antireflux therapy. This clinical review is simply an evidence-based overview addressing the indications, limitations, and recommended protocol for the clinical use of pH-MII in children.
双 pH 多通道腔内阻抗(pH-MII)是评估胃食管反流病(GERD)的敏感工具,特别适用于检测非酸性反流事件。pH-MII 技术在餐后或胃内容物非酸性时特别有用。最近,北美儿童胃肠病学、肝病学和营养学学会以及欧洲儿童胃肠病学、肝病学和营养学学会认识到,pH-MII 优于单独 pH 监测,可用于评估症状与胃食管反流之间的时间关系。在儿童中,pH-MII 可用于将症状与反流(特别是非酸性反流)相关联,定量评估管饲和餐后期间的反流,并评估抗反流治疗的疗效。本临床综述只是一个基于证据的概述,介绍了 pH-MII 在儿童中的临床应用的适应证、局限性和推荐方案。