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子宫颈癌:磁共振成像术前分期

[Uterine cervical cancer : preoperative staging with magnetic resonance imaging].

作者信息

Collettini F, Hamm B

机构信息

Klinik für Radiologie, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Deutschland.

出版信息

Radiologe. 2011 Jul;51(7):589-95. doi: 10.1007/s00117-010-2119-1.

DOI:10.1007/s00117-010-2119-1
PMID:21688026
Abstract

The treatment of uterine cervical carcinoma is largely dependent on the tumor stage. Despite significant inaccuracies in the clinical examination, uterine cervical cancer remains the only gynecological form of cancer still largely staged according to clinical findings. Although imaging is still not included in the staging the recently published revised FIGO (Fédération International de Gynécologie et d'Obstétrique) system encourages the use of modern cross-sectional imaging (magnetic resonance imaging MRI and computed tomography CT). Due to its high soft tissue contrast MRI allows excellent non-invasive assessment of the cervix with direct tumor delineation as well as assessment of the prognosis based on morphological factors. Studies in the literature report an accuracy of 93% for MRI in the preoperative assessment of tumor size and in the differentiation of operable from advanced cervical cancer. Therefore MRI is considered to be the optimal modality for diagnostic evaluation starting from FIGO stage IB1, for radiation therapy planning, and for exclusion of recurrence in follow-up. In this paper we give an overview of the role of magnetic resonance imaging in preoperative staging of uterine cervical cancer.

摘要

子宫颈癌的治疗很大程度上取决于肿瘤分期。尽管临床检查存在显著的不准确性,但子宫颈癌仍然是目前唯一主要依据临床检查结果进行分期的妇科癌症。虽然影像学检查仍未被纳入分期,但最近发布的修订版国际妇产科联盟(FIGO)系统鼓励使用现代横断面成像技术(磁共振成像MRI和计算机断层扫描CT)。由于MRI具有高软组织对比度,它能够对子宫颈进行出色的无创评估,直接勾勒肿瘤轮廓,并基于形态学因素评估预后。文献研究报告称,MRI在术前评估肿瘤大小以及区分可手术的子宫颈癌与晚期子宫颈癌方面的准确率为93%。因此,从FIGO 1B1期开始,MRI被认为是用于诊断评估、放射治疗计划制定以及随访中排除复发情况的最佳检查方式。在本文中,我们将概述磁共振成像在子宫颈癌术前分期中的作用。

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Br J Radiol. 2019 Feb;92(1094):20180293. doi: 10.1259/bjr.20180293. Epub 2018 Nov 1.
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本文引用的文献

1
Role of magnetic resonance imaging as an adjunct to clinical staging in cervical carcinoma.磁共振成像在宫颈癌临床分期中的辅助作用。
J Comput Assist Tomogr. 2010 Nov-Dec;34(6):855-64. doi: 10.1097/RCT.0b013e3181ed3090.
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[Pretreatment diagnostic evaluation of cervical cancer].[宫颈癌的预处理诊断评估]
Rofo. 2009 May;181(5):433-40. doi: 10.1055/s-0028-1109196. Epub 2009 Apr 16.
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Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium.国际妇产科联盟(FIGO)对外阴癌、宫颈癌和子宫内膜癌分期的修订版。
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Early invasive cervical cancer: MRI and CT predictors of lymphatic metastases in the ACRIN 6651/GOG 183 intergroup study.早期浸润性宫颈癌:ACRIN 6651/GOG 183组间研究中淋巴结转移的MRI和CT预测因素
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The performance of magnetic resonance imaging in early cervical carcinoma: a long-term experience.磁共振成像在早期宫颈癌中的应用:长期经验
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6
Correlations between dynamic contrast-enhanced magnetic resonance imaging-derived measures of tumor microvasculature and interstitial fluid pressure in patients with cervical cancer.宫颈癌患者肿瘤微血管的动态对比增强磁共振成像衍生测量值与组织间液压力之间的相关性
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7
Cervical cancer: value of an endovaginal coil magnetic resonance imaging technique in detecting small volume disease and assessing parametrial extension.宫颈癌:阴道内线圈磁共振成像技术在检测小体积病变及评估宫旁组织浸润中的价值
Gynecol Oncol. 2006 Jul;102(1):80-5. doi: 10.1016/j.ygyno.2005.11.038. Epub 2006 Jan 19.
8
Can MRI rule out bladder and rectal invasion in cervical cancer to help select patients for limited EUA?磁共振成像(MRI)能否排除宫颈癌的膀胱和直肠侵犯,以帮助选择适合进行有限范围的术中评估(EUA)的患者?
Gynecol Oncol. 2006 May;101(2):244-9. doi: 10.1016/j.ygyno.2005.10.012. Epub 2005 Nov 28.
9
Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervix.子宫颈癌的表观扩散系数:与正常子宫颈的比较。
Eur Radiol. 2005 Jan;15(1):71-8. doi: 10.1007/s00330-004-2529-4. Epub 2004 Nov 5.
10
Imaging in cervical cancer.宫颈癌的影像学检查
Cancer. 2003 Nov 1;98(9 Suppl):2028-38. doi: 10.1002/cncr.11679.