School of Health Sciences, University of Tampere, Tampere, Finland.
Acta Paediatr. 2011 Dec;100(12):1596-602. doi: 10.1111/j.1651-2227.2011.02387.x.
This study assessed whether adolescents' socioeconomic background, health and health behaviours are associated with later risk of poisoning hospitalization.
A prospective cohort of 54,169 Finns aged 14-18 years was followed for an average of 10.6 years. The end-point of the study was poisoning hospitalization, death or termination of follow-up in 2001. The relationships of socioeconomic background, health and health behaviour characteristics with poisoning hospitalization were studied with adjusted Cox's proportional hazard model.
We identified 443 persons (0.8%) with a diagnosed poisoning leading to hospital admission. The mean age at the time of the poisoning hospitalization was 22.7 years. The strongest risk factors for poisoning hospitalization in males were more than three stress symptoms weekly (HR 1.9), poor school success (HR 1.9) and not living with both of the parents in adolescence (HR 1.8). In females, the strongest risk factors were more than three stress symptoms weekly (HR 2.1), poor school success (HR 2.2) and recurring drunkenness as drinking style (HR 1.7).
Poor school performance, health and health-compromising behaviour adopted in adolescence are associated with a poisoning hospitalization risk in adulthood. Daily smoking and recurring drunkenness were strongly associated with a later poisoning hospitalization.
本研究旨在评估青少年的社会经济背景、健康状况和行为与日后中毒住院风险的关系。
对平均年龄为 14-18 岁的 54169 名芬兰青少年进行前瞻性队列研究，随访时间平均为 10.6 年。研究终点为中毒住院、死亡或 2001 年随访结束。采用校正后的 Cox 比例风险模型，研究社会经济背景、健康和健康行为特征与中毒住院的关系。
我们发现 443 人（0.8%）因中毒导致住院。中毒住院时的平均年龄为 22.7 岁。男性中毒住院的最强危险因素是每周出现超过三个压力症状（HR 1.9）、学业成绩不佳（HR 1.9）和青春期未与父母双方同住（HR 1.8）。对于女性，最强的危险因素是每周出现超过三个压力症状（HR 2.1）、学业成绩不佳（HR 2.2）和酗酒作为饮酒方式（HR 1.7）。
青少年时期表现不佳的学业成绩、健康状况和危害健康的行为与成年后中毒住院风险有关。每日吸烟和反复酗酒与日后中毒住院有很强的相关性。
