甲状腺激素对维甲酸诱导小鼠乳腺肿瘤病毒表达的需求。
Thyroid hormone requirement for retinoic acid induction of mouse mammary tumor virus expression.
作者信息
Bolander F F, Blackstone M E
机构信息
Department of Biological Sciences, University of South Carolina, Columbia 29208.
出版信息
J Virol. 1990 Oct;64(10):5192-3. doi: 10.1128/JVI.64.10.5192-5193.1990.
Abstract
In normal mouse mammary epithelium, insulin, cortisol, and prolactin are absolute requirements for mouse mammary tumor virus expression. Retinoic acid further increased mouse mammary tumor virus expression two- to threefold but only when triiodothyronine was also present; neither retinoic acid nor triiodothyronine alone had any effect.
摘要
在正常小鼠乳腺上皮中，胰岛素、皮质醇和催乳素是小鼠乳腺肿瘤病毒表达的绝对必需物质。视黄酸可使小鼠乳腺肿瘤病毒表达进一步增加2至3倍，但前提是同时存在三碘甲状腺原氨酸；单独使用视黄酸或三碘甲状腺原氨酸均无任何作用。
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