Department of Biology, University of California, Riverside, CA 92521, USA.
Proc Natl Acad Sci U S A. 2011 Jun 28;108 Suppl 2(Suppl 2):10800-7. doi: 10.1073/pnas.1100304108. Epub 2011 Jun 20.
Diverse bacterial lineages form beneficial infections with eukaryotic hosts. The origins, evolution, and breakdown of these mutualisms represent important evolutionary transitions. To examine these key events, we synthesize data from diverse interactions between bacteria and eukaryote hosts. Five evolutionary transitions are investigated, including the origins of bacterial associations with eukaryotes, the origins and subsequent stable maintenance of bacterial mutualism with hosts, the capture of beneficial symbionts via the evolution of strict vertical transmission within host lineages, and the evolutionary breakdown of bacterial mutualism. Each of these transitions has occurred many times in the history of bacterial-eukaryote symbiosis. We investigate these evolutionary events across the bacterial domain and also among a focal set of well studied bacterial mutualist lineages. Subsequently, we generate a framework for examining evolutionary transitions in bacterial symbiosis and test hypotheses about the selective, ecological, and genomic forces that shape these events.
不同的细菌谱系与真核宿主形成有益的感染。这些共生关系的起源、进化和破裂代表了重要的进化转变。为了研究这些关键事件，我们综合了来自细菌与真核宿主之间各种相互作用的数据。研究了五个进化转变，包括细菌与真核生物共生关系的起源、细菌与宿主共生关系的起源和随后的稳定维持、通过宿主谱系内严格垂直传播的进化捕获有益共生体，以及细菌共生关系的进化破裂。在细菌-真核共生关系的历史中，这些转变已经发生了很多次。我们在细菌领域内以及在一组经过充分研究的细菌共生体谱系中研究了这些进化事件。随后，我们生成了一个框架来研究细菌共生关系中的进化转变，并检验关于塑造这些事件的选择、生态和基因组力量的假设。
