男性芳香酶抑制剂：作用与治疗选择。
Aromatase inhibitors in men: effects and therapeutic options.
机构信息
Department of Internal Medicine, Erasmus university Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
出版信息
Reprod Biol Endocrinol. 2011 Jun 21;9:93. doi: 10.1186/1477-7827-9-93.
Abstract
Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic short stature and constitutional delay of puberty. Long-term efficacy and safety of the use of aromatase inhibitors has not yet been established in males, however, and their routine use is therefore not yet recommended.
摘要
芳香酶抑制剂能有效延缓男孩骨骼成熟并提高成年男性的睾酮水平。因此，芳香酶抑制剂可能被用于治疗促性腺激素依赖性性早熟、特发性身材矮小和体质性青春期延迟的男孩，以增加其成年身高。然而，男性使用芳香酶抑制剂的长期疗效和安全性尚未确定，因此不建议常规使用。
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