Rerksuppaphol Sanguansak, Rerksuppaphol Lakkana
Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
J Med Assoc Thai. 2011 Jun;94(6):710-5.
To evaluate the prevalence and risk factor of dyslipidemia in Thai schoolchildren.
A cross section- study of 348 schoolchildren aged 6-17.8 years in Nakork Nayok province, Thailand between May and June 2009 was conducted. Total cholesterol and triglyceride were measured from a 10-hour fasting blood. Dyslipidemia (hypercholesterolemia and/or hypertriglyceridemia) was defined according to the American Academy of Pediatrics AAP) guidelines. Demographic and anthropometric data were recorded. Odds ratio and 95% confidence interval were used to compare the prevalence of dyslipidemia.
The prevalence of hypercholesterolemia and hypertriglyceridemia were 1.2% and 10.6%, respectively, with none of the children who simultaneously had high cholesterol and triglyceride levels. Overweight, obesity and thinness were defined in 34 (9.8%), 34 (9.8%) and 25 (7.2%) children, respectively. Odds ratio ofhaving dyslipidemia in overweight and/or obese children compared to non-obese children was 4.0 (95% CI 2.0-8.0). Odd ratios ofhaving dyslipidemia were not significant differences by other risk factors such as gender [1.2 (0.6-2.2)], age [1.3 (0.7-2.5)], hypertension [0.9 (0.2-4.2)], family history of dyslipidemia [2.4 (0.6-8.0)], family history of diabetes mellitus [0.5 (0.1-2.1)], presence ofa smoker in the family [1.5 (0.8-3.1)] and differentABO blood types.
The overall prevalence of dyslipidemia in Thai schoolchildren was 11.8%. Overweight and/or obesity were the sole risk factor for dyslipidemia in Thai schoolchildren aged 6-17.8 years.
评估泰国学龄儿童血脂异常的患病率及危险因素。
于2009年5月至6月对泰国那空那育府348名年龄在6至17.8岁的学龄儿童进行了一项横断面研究。从禁食10小时的血液中测量总胆固醇和甘油三酯。血脂异常(高胆固醇血症和/或高甘油三酯血症)根据美国儿科学会(AAP)指南定义。记录人口统计学和人体测量数据。采用比值比和95%置信区间比较血脂异常的患病率。
高胆固醇血症和高甘油三酯血症的患病率分别为1.2%和10.6%,没有儿童同时存在高胆固醇和高甘油三酯水平。分别有34名(9.8%)、34名(9.8%)和25名(7.2%)儿童被定义为超重、肥胖和消瘦。与非肥胖儿童相比,超重和/或肥胖儿童血脂异常的比值比为4.0(95%CI 2.0 - 8.0)。其他危险因素如性别[1.2(0.6 - 2.2)]、年龄[1.3(0.7 - 2.5)]、高血压[0.9(0.2 - 4.2)]、血脂异常家族史[2.4(0.6 - 8.0)]、糖尿病家族史[0.5(0.1 - 2.1)]、家庭中有吸烟者[1.5(0.8 - 3.1)]以及不同的ABO血型,其血脂异常比值比无显著差异。
泰国学龄儿童血脂异常的总体患病率为11.8%。超重和/或肥胖是6至17.8岁泰国学龄儿童血脂异常的唯一危险因素。