Rangwala Sophia, Hunt Christine, Modi Gunjan, Krishnan Bhuvaneswari, Orengo Ida
Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
Dermatol Online J. 2011 Jun 15;17(6):8.
Amelanotic subungual melanoma (SUM) is difficult to clinically diagnose owing to its rarity and variable presentation. We describe a case of a 63-year-old gentleman with an amelanotic SUM that developed after local trauma and presented as a persistent non-healing ulcer which was initially mistaken for a chronic infection. Because amelanotic SUM can mimic other lesions, the physician should have a high index of suspicion for SUM when managing atypical nail lesions to ensure prompt recognition and treatment. The prior trauma to the nail also suggests that posttraumatic inflammation may play a role in SUM development.
无色素性甲下黑色素瘤(SUM)因其罕见性和表现多样,临床上难以诊断。我们描述了一例63岁男性患者,患有无色素性SUM,该疾病在局部创伤后发生,表现为持续性不愈合溃疡,最初被误诊为慢性感染。由于无色素性SUM可模仿其他病变,医生在处理非典型指甲病变时应高度怀疑SUM,以确保及时识别和治疗。指甲先前的创伤也表明创伤后炎症可能在SUM的发生中起作用。