Feldman N, Skoll A, Sibai B
Department of Obstetrics and Gynecology, University of Tennessee, Memphis.
Am J Obstet Gynecol. 1990 Sep;163(3):855-8. doi: 10.1016/0002-9378(90)91083-o.
To determine the incidence of fetomaternal hemorrhage in patients undergoing cesarean section, Kleihauer-Betke tests were performed in the immediate postoperative period on 199 parturients. Some degree of hemorrhage was detected in 18.5% of patients, with 2.5% demonstrating greater than 30 ml of fetal blood. Comparison of groups on the basis of indication for cesarean delivery revealed no difference in rates of fetal hemorrhage. Because patients with greater than 30 ml of fetal blood would not be adequately protected from Rh sensitization by the standard 300 micrograms dose of Rh immune globulin, we recommend screening all Rh-negative patients undergoing cesarean section for the presence of significant fetomaternal hemorrhage.
为确定剖宫产患者母胎输血的发生率，对199名产妇在术后即刻进行了 Kleihauer-Betke 试验。18.5%的患者检测到一定程度的出血，2.5%的患者显示胎儿出血量超过30毫升。根据剖宫产指征对各组进行比较，发现胎儿出血率无差异。由于标准剂量300微克的 Rh 免疫球蛋白无法充分保护胎儿出血量超过30毫升的患者免于 Rh 致敏，我们建议对所有接受剖宫产的 Rh 阴性患者进行筛查，以确定是否存在显著的母胎输血。
