Department of Primary Care and Public Health, School of Public Health, Imperial College London, Reynolds Building, St Dunstan's Road, London W6 8RP, UK.
Alcohol Alcohol. 2011 Sep-Oct;46(5):607-13. doi: 10.1093/alcalc/agr072. Epub 2011 Jun 22.
The purpose of this prospective study was to determine how subjective measures of binge drinking predict suboptimal subjective health. In order to contribute to the understanding of potential causal mechanisms, we also aimed to determine the factors through which subjective health predicts alcohol-specific hospitalizations.
A total of 16,111 alcohol-drinking men and women, aged 20-54 years, participated in the Health and Social Support baseline postal survey in 1998, and also responded to the repeated measurement 5 years later in 2003 (T2). Suboptimal subjective health was defined as self-reported overall health status being fair, rather poor or poor. Subjective measures of binge drinking were frequency of subjective intoxications/drunkenness, frequency of hangovers and frequency of alcohol-induced pass-outs.
Frequency of intoxications, hangovers and alcohol-induced pass-outs, all predicted suboptimal subjective health regardless of several potential confounders, including beverage-specific total intake. Those reporting suboptimal subjective health at baseline had a 5-fold odds ratio (5.08, 95% confidence interval: 3.43, 6.48) for alcohol-related hospitalizations, compared with those rating their health above fair, when gender and age were controlled. Binge drinking, together with concurrent symptoms of depression, explained over 50% of this relationship, and when additionally taking into account smoking, over two-thirds of this relation was explained.
Mental health is an important mediating factor between binge drinking, suboptimal subjective health and alcohol-specific hospitalizations, and symptoms of depression should therefore be taken into account in prevention of alcohol-related adverse health outcomes.
本前瞻性研究旨在确定暴饮的主观测量如何预测不佳的主观健康。为了有助于理解潜在的因果机制,我们还旨在确定通过哪些因素主观健康预测特定于酒精的住院治疗。
共有 16111 名年龄在 20-54 岁之间的饮酒男性和女性参加了 1998 年的健康和社会支持基线邮寄调查,并在 5 年后的 2003 年(T2)再次回复。主观健康不佳定义为自我报告的整体健康状况为一般、较差或差。暴饮的主观测量包括主观醉酒/醉酒的频率、宿醉的频率和酒精引起的昏迷的频率。
无论是否存在几种潜在的混杂因素,包括特定饮料的总摄入量,醉酒、宿醉和酒精引起的昏迷的频率都预测了不佳的主观健康。与自评健康状况好于一般的人相比,基线时报告不佳主观健康的人因酒精相关住院治疗的比值比为 5.08(95%置信区间:3.43,6.48),当控制性别和年龄时。与同时存在的抑郁症状一起,暴饮解释了这种关系的 50%以上,当进一步考虑吸烟时,这种关系的三分之二以上得到了解释。
心理健康是暴饮、不佳主观健康和特定于酒精的住院治疗之间的一个重要中介因素,因此在预防与酒精相关的不良健康结果时,应考虑抑郁症状。