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A synonymous change in the influenza A virus neuraminidase gene interferes with PCR-based subtyping and oseltamivir resistance mutation detection.

作者信息

Trevino Christina, Bihon Selamawit, Pinsky Benjamin A

出版信息

J Clin Microbiol. 2011 Aug;49(8):3101-2. doi: 10.1128/JCM.00642-11. Epub 2011 Jun 22.

DOI:10.1128/JCM.00642-11
PMID:21697334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3147745/
Abstract
摘要

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A synonymous change in the influenza A virus neuraminidase gene interferes with PCR-based subtyping and oseltamivir resistance mutation detection.甲型流感病毒神经氨酸酶基因中的同义变化会干扰基于聚合酶链反应的亚型分型和奥司他韦耐药性突变检测。
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本文引用的文献

1
Ultrasensitive detection of drug-resistant pandemic 2009 (H1N1) influenza A virus by rare-variant-sensitive high-resolution melting-curve analysis.高分辨率熔解曲线分析技术对罕见变异敏感的方法用于检测耐药性大流行 2009(H1N1)流感 A 病毒的超灵敏检测
J Clin Microbiol. 2011 Jul;49(7):2602-9. doi: 10.1128/JCM.00277-11. Epub 2011 May 4.
2
Development of a real-time RT-PCR assay for detection of resistance to oseltamivir in influenza A pandemic (H1N1) 2009 virus using single nucleotide polymorphism probes.利用单核苷酸多态性探针实时 RT-PCR 检测方法检测流感 A 病毒(H1N1)2009 株对奥司他韦的耐药性
J Virol Methods. 2011 May;173(2):259-65. doi: 10.1016/j.jviromet.2011.02.014. Epub 2011 Feb 22.
3
Identification of oseltamivir resistance among pandemic and seasonal influenza A (H1N1) viruses by an His275Tyr genotyping assay using the cycling probe method.环介导等温扩增法 His275Tyr 基因分型检测对大流行和季节性流感 A(H1N1)病毒奥司他韦耐药性的鉴定。
J Clin Microbiol. 2011 Jan;49(1):125-30. doi: 10.1128/JCM.01401-10. Epub 2010 Nov 17.
4
The validation of a real-time RT-PCR assay which detects influenza A and types simultaneously for influenza A H1N1 (2009) and oseltamivir-resistant (H275Y) influenza A H1N1 (2009).用于同时检测流感 A 型和甲型 H1N1(2009)以及奥司他韦耐药(H275Y)甲型 H1N1(2009)的实时 RT-PCR 检测方法的验证。
J Virol Methods. 2011 Jan;171(1):86-90. doi: 10.1016/j.jviromet.2010.10.005. Epub 2010 Oct 14.
5
Simplified screening method for detecting oseltamivir resistant pandemic influenza A (H1N1) 2009 virus by a RT-PCR/restriction fragment length polymorphism assay.通过 RT-PCR/限制性片段长度多态性分析的简化方法检测奥司他韦耐药的大流行流感 A(H1N1)2009 病毒。
J Virol Methods. 2010 Dec;170(1-2):165-8. doi: 10.1016/j.jviromet.2010.09.005. Epub 2010 Sep 15.
6
Diagnostic accuracy of an allele-specific reverse transcriptase-PCR assay targeting the H275Y oseltamivir resistant mutation in 2009 pandemic influenza A/H1N1 virus.针对 2009 年大流行流感 A/H1N1 病毒 H275Y 奥司他韦耐药突变的等位基因特异性逆转录酶 PCR 检测方法的诊断准确性。
J Clin Virol. 2010 Sep;49(1):21-5. doi: 10.1016/j.jcv.2010.06.019. Epub 2010 Jul 31.
7
The detection of oseltamivir-resistant pandemic influenza A/H1N1 2009 viruses using a real-time RT-PCR assay.采用实时 RT-PCR 检测方法检测奥司他韦耐药的大流行流感 A/H1N1 2009 病毒。
J Virol Methods. 2010 Oct;169(1):47-51. doi: 10.1016/j.jviromet.2010.06.014. Epub 2010 Jun 30.
8
Detection of the rapid emergence of the H275Y mutation associated with oseltamivir resistance in severe pandemic influenza virus A/H1N1 09 infections.检测与奥司他韦耐药相关的 H275Y 突变在严重大流行流感病毒 A/H1N1 09 感染中的快速出现。
Antiviral Res. 2010 Jul;87(1):16-21. doi: 10.1016/j.antiviral.2010.04.002. Epub 2010 Apr 10.
9
Rapid detection of influenza A pandemic (H1N1) 2009 virus neuraminidase resistance mutation H275Y by real-time reverse transcriptase PCR.实时逆转录聚合酶链反应快速检测 2009 年甲型流感(H1N1)病毒神经氨酸酶耐药突变 H275Y。
J Clin Microbiol. 2010 May;48(5):1884-7. doi: 10.1128/JCM.02540-09. Epub 2010 Mar 10.
10
Evaluation of a rapid molecular algorithm for detection of pandemic influenza A (H1N1) 2009 virus and screening for a key oseltamivir resistance (H275Y) substitution in neuraminidase.评估一种用于检测大流行性流感 A(H1N1)2009 病毒的快速分子算法,以及筛选神经氨酸酶中的关键奥司他韦耐药(H275Y)取代。
J Clin Virol. 2010 Jan;47(1):34-7. doi: 10.1016/j.jcv.2009.09.030. Epub 2009 Oct 25.