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外伤性脑损伤所致垂体功能减退症的当前理解和管理宣言。

Manifesto for the current understanding and management of traumatic brain injury-induced hypopituitarism.

机构信息

Erciyes University Medical School, Department of Endocrinology, Kayseri, Turkey.

出版信息

J Endocrinol Invest. 2011 Jul-Aug;34(7):541-3. doi: 10.3275/7805. Epub 2011 Jun 21.

DOI:10.3275/7805
PMID:21697650
Abstract

Traumatic brain injury (TBI)-induced hypopituitarism remains a relevant medical problem, because it may affect a significant proportion of the population. In the last decade important studies have been published investigating pituitary dysfunction after TBI. Recently, a group of experts gathered and revisited the topic of TBI-induced hypopituitarism. During the 2-day meeting, the main issues of this topic were presented and discussed, and current understanding and management of TBI-induced hypopituitarism are summarized here.

摘要

创伤性脑损伤(TBI)引起的垂体功能减退仍然是一个相关的医学问题,因为它可能影响相当一部分人群。在过去的十年中,已经发表了许多重要的研究,探讨了 TBI 后的垂体功能障碍。最近,一组专家聚集在一起重新讨论了 TBI 引起的垂体功能减退的问题。在为期两天的会议中,提出并讨论了这个主题的主要问题,并在这里总结了目前对 TBI 引起的垂体功能减退的认识和管理。

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Effect of growth hormone replacement therapy on cognition after traumatic brain injury.生长激素替代疗法对颅脑损伤后认知功能的影响。
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Psychiatric and neuropsychological changes in growth hormone-deficient patients after traumatic brain injury in response to growth hormone therapy.
Nat Rev Endocrinol. 2021 Feb;17(2):114-129. doi: 10.1038/s41574-020-00437-2. Epub 2020 Nov 27.
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Clinical picture and the treatment of TBI-induced hypopituitarism.颅脑损伤后垂体功能减退症的临床特征及治疗。
Pituitary. 2019 Jun;22(3):261-269. doi: 10.1007/s11102-019-00956-w.
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Pituitary dysfunction due to sports-related traumatic brain injury.因运动相关创伤性脑损伤导致的垂体功能障碍。
Pituitary. 2019 Jun;22(3):322-331. doi: 10.1007/s11102-019-00937-z.
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Chronic Hypopituitarism Associated with Increased Postconcussive Symptoms Is Prevalent after Blast-Induced Mild Traumatic Brain Injury.爆炸所致轻度创伤性脑损伤后,与脑震荡后症状增加相关的慢性垂体功能减退很常见。
Front Neurol. 2018 Feb 19;9:72. doi: 10.3389/fneur.2018.00072. eCollection 2018.
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The Development of Neuroendocrine Disturbances over Time: Longitudinal Findings in Patients after Traumatic Brain Injury and Subarachnoid Hemorrhage.神经内分泌紊乱随时间的发展:创伤性脑损伤和蛛网膜下腔出血患者的纵向研究结果
Int J Mol Sci. 2015 Dec 22;17(1):2. doi: 10.3390/ijms17010002.
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J Endocrinol Invest. 2010 Dec;33(11):770-5. doi: 10.1007/BF03350340. Epub 2010 May 17.
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