ESGO Task Force for Fertility Preservation in Gynecological Cancer, Geneva, Switzerland.
Int J Gynecol Cancer. 2011 Jul;21(5):951-63. doi: 10.1097/IGC.0b013e31821bec6b.
In young patients with borderline ovarian tumor a conservative treatment approach does not seem to have a significant impact on survival, and the outcome regarding fertility is good in general. It can be considered even if noninvasive peritoneal implants are discovered at the time of the initial surgery. In contrast, in patients with epithelial ovarian cancer, conservative surgery should be considered only in adequately staged patients, with a stage IA grade 1 (and probably 2) serous, mucinous or an endometrioid tumor, including a careful follow-up. Such an approach could also probably be discussed in stage IC grade 1 disease.In patients with nonepithelial malignant ovarian tumors, conservative surgery is also feasible, particularly in patients with malignant germ cell tumors because of their high chemosensitivity leading to an excellent prognosis in general.
在年轻的交界性卵巢肿瘤患者中，保守治疗方法似乎对生存没有显著影响，而且总体上生育结局良好。即使在初始手术时发现了非浸润性腹膜种植，也可以考虑这种方法。相比之下，在患有上皮性卵巢癌的患者中，只有在充分分期的患者中才应考虑保守性手术，分期为 IA 级 1（可能还有 2）级浆液性、黏液性或子宫内膜样肿瘤，包括仔细的随访。这种方法也可能在 IC 期 1 级疾病中进行讨论。对于非上皮性恶性卵巢肿瘤患者，保守性手术也是可行的，特别是对于恶性生殖细胞肿瘤患者，因为它们对化疗高度敏感，总体预后良好。
