Molecular biology. A new twist for topoisomerase.
作者信息
Cerritelli Susana M, Chon Hyongi, Crouch Robert J
机构信息
Program in Genomics of Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Science. 2011 Jun 24;332(6037):1510-1. doi: 10.1126/science.1208450.
Abstract
摘要
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Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.拓扑异构酶 1 在酿酒酵母高转录时引发重复序列形成短缺失。
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Role for topoisomerase 1 in transcription-associated mutagenesis in yeast.拓扑异构酶 1 在酵母转录相关诱变中的作用。
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Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}.滞后链复制错误的差异校正，由 DNA 聚合酶α和δ造成。
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