Katayama Kayoko, Wang Meihua, Ogawa Namiko, Ikehara Satoyo, Liu Chun-Yan, Xia Mu-Qun, Machida Kazuhiko
Department of Preventive Medicine and Health, Welfare and Medical Policy, Graduate School of Human Sciences Waseda University, Yokohama-city, Kanagawa, Japan.
Nihon Eiseigaku Zasshi. 2011 May;66(3):573-81. doi: 10.1265/jjh.66.573.
In this study, we investigated the relationships of neutrophil functions with lifestyle factors (namely, subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived status health) and health behavior in the Chinese urban elderly.
We performed a health survey of the elderly aged 65 years or older living in Tianjin. The subjects were 42 males (69.1 ± 4.1 years old) and 41 females (69.1 ± 4.1 years old). Investigations of subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived health status were performed. The phagocytosis and superoxide productivity of neutrophils were measured by the nitroblue tetrazolium (NBT) reduction method. In addition, leukocyte count and serum total protein (TP) level were examined.
The investigations revealed the associations of health behavior (p<0.05) and self-perceived health (p<0.10) with the balance between phagocytosis and subsequent superoxide production.
The present study revealed that there were correlations of neutrophil functions with lifestyle factors (subjective stress, exercise habits, smoking habits, alcohol-drinking habits, and self-perceived status health) and health behavior in the Chinese urban elderly.
在本研究中,我们调查了中国城市老年人中性粒细胞功能与生活方式因素(即主观压力、运动习惯、吸烟习惯、饮酒习惯和自我感知健康状况)及健康行为之间的关系。
我们对居住在天津的65岁及以上老年人进行了健康调查。受试者包括42名男性(69.1±4.1岁)和41名女性(69.1±4.1岁)。对主观压力、运动习惯、吸烟习惯、饮酒习惯和自我感知健康状况进行了调查。采用硝基蓝四唑(NBT)还原法测定中性粒细胞的吞噬作用和超氧化物生成能力。此外,还检测了白细胞计数和血清总蛋白(TP)水平。
调查揭示了健康行为(p<0.05)和自我感知健康(p<0.10)与吞噬作用和随后超氧化物生成之间平衡的关联。
本研究表明,中国城市老年人中性粒细胞功能与生活方式因素(主观压力、运动习惯、吸烟习惯、饮酒习惯和自我感知健康状况)及健康行为之间存在相关性。