Pereverzev V A, Kubarko A I
Fiziol Zh SSSR Im I M Sechenova. 1990 Apr;76(4):528-33.
Experiments on white rats and mice have shown that intraventricular administration of serotonin (10 mg) or intraabdominal administration of histamine (0.5 mg/kg) do not affect body temperature, whereas simultaneous administration of these drugs leads to a reliable drop of body temperature due to intensification of the heat output and the inhibition of heat production. These biogenic amines seem to act as the substances with additive hypothermal properties and, probably, are the components of natural antipyretic system of the warm-blooded organism.
对白鼠和小鼠的实验表明，脑室内注射血清素（10毫克）或腹腔注射组胺（0.5毫克/千克）不会影响体温，而同时注射这些药物会导致体温可靠下降，这是由于散热增强和产热受到抑制。这些生物胺似乎作为具有相加降温特性的物质起作用，并且可能是温血动物天然解热系统的组成部分。
