Hernández-Fernández Francisco, Fernández-Díaz Eva, Pardal-Fernández Jose M, Segura Tomás, García-García Jorge
Department of Neurology, Complejo Hospitalario Universitario de Albacete (Hermanos Falcó,37), Albacete (Postal code: 02/2006), Spain.
Int Arch Med. 2011 Jun 25;4(1):23. doi: 10.1186/1755-7682-4-23.
Periodic Lateralized Epileptiform Discharges (PLEDs) are usually seen in the context of destructive structural lesions of the cortex, more frequently in acute ischemic stroke and less common in tumours and meningoencephalitis, specially herpes simplex virus. Its origin and prognosis are uncertain but it is known that PLEDs are linked to epilectic seizures, including status epilepticus.We report on a 75-year old woman with pneumococcal meningoencephalitis who presented altered level of consciousness, acute focal deficits, convulsive seizures and PLEDs in left hemisphere. The finding of PLEDs on the electroencephalogram is related to focal lesions of heterogeneous origin, which up to date, have not been documented in pneumococcal infections of the central nervous system. Our case highlights the importance of identifying and addressing any modifiable etiologic factors of PLEDs.
周期性一侧性癫痫样放电（PLEDs）通常出现在皮质破坏性结构性病变的背景下，在急性缺血性卒中中更常见，而在肿瘤和脑膜脑炎（特别是单纯疱疹病毒性脑膜脑炎）中较少见。其起源和预后尚不确定，但已知PLEDs与癫痫发作（包括癫痫持续状态）有关。我们报告了一名75岁患有肺炎球菌性脑膜脑炎的女性，她出现意识水平改变、急性局灶性缺损、惊厥发作以及左半球的PLEDs。脑电图上发现PLEDs与多种起源的局灶性病变有关，而迄今为止，中枢神经系统肺炎球菌感染中尚未有相关记录。我们的病例强调了识别和处理PLEDs任何可改变病因因素的重要性。
