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一例以PLEDS为特征的神经白塞病性脑炎,与单纯疱疹病毒性脑炎相鉴别:病例报告

A case of neuro-Behçet's encephalitis with pleds as distinct from herpes simplex encephalitis: a differential diagnosis.

作者信息

Kihara M, Takahashi M, Mitsui Y, Tanaka H, Nishikawa S, Nakamura Y

机构信息

Department of Neurology, Kinki University School of Medicine, Osaka, Japan.

出版信息

Funct Neurol. 1996 Mar-Jun;11(2-3):99-103.

PMID:8765757
Abstract

We report a male patient with neuro-Behçet's disease who had somnolence, mild motor aphasia and periodic lateralized epileptiform discharge. SPECT study showed decreased cerebral blood flow in the left frontal and temporal lobes. An MRI scan of the head showed only mild brain stem atrophy. His clinical signs were markedly improved after administration of prednisolone. We propose that some cases of neuro-Beh,cet's disease may have very similar clinical features to herpes simplex encephalitis and that SPECT and MRI examinations can be very useful in distinguishing the ischemic lesion of neuro-Behçet's from the inflammatory lesion of herpes simplex encephalitis.

摘要

我们报告了一名患有神经白塞病的男性患者,该患者出现嗜睡、轻度运动性失语和周期性一侧性癫痫样放电。单光子发射计算机断层扫描(SPECT)研究显示左额叶和颞叶脑血流量减少。头部磁共振成像(MRI)扫描仅显示轻度脑干萎缩。给予泼尼松龙后,他的临床症状明显改善。我们提出,一些神经白塞病病例可能具有与单纯疱疹性脑炎非常相似的临床特征,并且SPECT和MRI检查对于区分神经白塞病的缺血性病变与单纯疱疹性脑炎的炎性病变非常有用。

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