Rousselot-Pailley B, Fortin C, Golse B, Falissard B, Robel L
Service de pédopsychiatrie de l'enfant et de l'adolescent, hôpital Necker-Enfants malades, 149-162, rue de Sèvres, 75015 Paris, France.
Encephale. 2011 Jun;37(3):191-8. doi: 10.1016/j.encep.2010.08.014. Epub 2010 Oct 22.
We have previously developed the FAQ self-report, an adaptation of the Baron-Cohen's Autism Quotient self-report, in order to detect traits of the autistic spectrum in the parents and siblings of children with autism. We have previously shown that parents of children with autism show significant differences in their global scores and in their social functioning scores according to their answers to the FAQ self-report.
Our aim was to validate the FAQ self-report in a population of control parents, and to confirm our previous results concerning parents of children with autism.
Hundred and twenty-seven adults (67 female, 60 male), parents of children with normal development were recruited in the general population. They were asked to fulfill the 40 questions of the FAQ self-report at two different times. Sixty-six parents of children with autism were asked to fulfill the FAQ self-report, for group comparisons. Statistical factor analysis and test-retest reliability analysis was performed with the Matlab toolbox(©) software.
Statistical factor analysis and test-retest reliability show that the FAQ is structured in two main factors, socialization and communication on one hand, rigidity and imagination on the other, with good test-retest reliability. Further comparison between parents of children with autism and control parents shows a significant difference between the two groups for the socialization and communication domain, and for the global score. We show for the first time that scores of the parents of children with autism remain unchanged from infancy to adulthood.
The FAQ is the first French validated self-report focused on the detection of traits of the autistic spectrum in parents and siblings of children with autism. It is structured in two main factors, corresponding to imagination/rigidity, which are negatively correlated, and communication and socialization, which are positively correlated. The FAQ is therefore a reliable instrument to measure endophenotypes associated with the autistic spectrum in parents of children with autism, and may be useful in genetic studies.
我们之前开发了常见问题自我报告（FAQ 自我报告），它是对巴伦 - 科恩自闭症商数自我报告的改编版本，用于检测自闭症儿童的父母及兄弟姐妹的自闭症谱系特征。我们之前已经表明，根据他们对 FAQ 自我报告的回答，自闭症儿童的父母在总体得分和社交功能得分上存在显著差异。
我们的目的是在对照父母群体中验证 FAQ 自我报告，并确认我们之前关于自闭症儿童父母的研究结果。
从普通人群中招募了 127 名成年人（67 名女性，60 名男性），他们是发育正常儿童的父母。要求他们在两个不同时间完成 FAQ 自我报告的 40 个问题。66 名自闭症儿童的父母也被要求完成 FAQ 自我报告，用于组间比较。使用 Matlab 工具箱（©）软件进行统计因子分析和重测信度分析。
统计因子分析和重测信度表明，FAQ 由两个主要因子构成，一方面是社交和沟通，另一方面是刻板和想象力，具有良好的重测信度。自闭症儿童父母与对照父母之间的进一步比较显示，两组在社交和沟通领域以及总体得分上存在显著差异。我们首次表明，自闭症儿童父母的得分从婴儿期到成年期保持不变。
FAQ 是首个经过法语验证的自我报告，专注于检测自闭症儿童的父母及兄弟姐妹的自闭症谱系特征。它由两个主要因子构成，分别对应想象力/刻板（二者呈负相关）以及沟通和社交（二者呈正相关）。因此，FAQ 是一种可靠的工具，可用于测量自闭症儿童父母中与自闭症谱系相关的内表型，并且可能在基因研究中有用。
