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心力衰竭门诊就诊的女性和男性患者的结局:一项为期 12 个月的纵向研究结果。

Outcomes for women and men who attend a heart failure clinic: results of a 12-month longitudinal study.

机构信息

School of Rehabilitation, Faculty of Medicine, University of Montreal, Montreal, Canada.

出版信息

J Card Fail. 2011 Jul;17(7):540-6. doi: 10.1016/j.cardfail.2011.03.001. Epub 2011 May 6.

DOI:10.1016/j.cardfail.2011.03.001
PMID:21703525
Abstract

BACKGROUND

Although prevalence of heart failure (HF) is similar in women and men, more men are admitted to specialized HF clinics, possibly owing to a perception that men benefit more. Our aim was to describe 1-year outcomes in men and women attending specialized HF clinics.

METHODS AND RESULTS

We enrolled 531 newly referred patients (mean age 66 years, 26% women) to 1 of 6 HF multidisciplinary clinics in Quebec. Data were collected at time of entry to the clinic and 6 and 12 months later. The 3 main outcomes, mortality, disease evolution (New York Heart Association functional class, quality of life, 6-minute walk), and number of hospital admissions/emergency department visits were analyzed separately. Survival was higher in women than in men (adjusted hazard ratio 2.53, 95% confidence interval 1.10-5.80). Both women and men improved over the 12-month period in terms of quality of life, 6-minute walk, and lower use of hospital and emergency department. Persons who at entry to the clinic had more severe disease showed more improvement. Deterioration over the year was associated with higher number of comorbidities, but not with age or gender.

CONCLUSIONS

Both men and women with HF who attend specialized HF clinics improved, including those with more severe disease.

摘要

背景

尽管心力衰竭(HF)的患病率在男性和女性中相似,但更多的男性被收入专门的 HF 诊所,这可能是因为人们认为男性受益更多。我们的目的是描述在专门的 HF 诊所就诊的男性和女性的 1 年结局。

方法和结果

我们招募了 531 名新转诊患者(平均年龄 66 岁,26%为女性)至魁北克的 6 家 HF 多学科诊所之一。数据在进入诊所时、6 个月和 12 个月后收集。主要结局包括死亡率、疾病进展(纽约心脏协会功能分级、生活质量、6 分钟步行距离)和住院/急诊就诊次数,分别进行分析。女性的生存率高于男性(调整后的危险比为 2.53,95%置信区间为 1.10-5.80)。在 12 个月的时间内,无论是女性还是男性,生活质量、6 分钟步行距离和住院/急诊就诊次数均有所改善。在进入诊所时疾病更严重的患者改善更为显著。一年内的病情恶化与合并症数量增加有关,但与年龄或性别无关。

结论

在专门的 HF 诊所就诊的男性和女性 HF 患者均有改善,包括那些病情更严重的患者。

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