淋巴细胞信号转导汇聚于微管。
Lymphocyte signaling converges on microtubules.
机构信息
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
出版信息
Immunity. 2011 Jun 24;34(6):825-7. doi: 10.1016/j.immuni.2011.06.004.
PMID:21703536
Abstract
Movement of immunoreceptor microclusters tunes lymphocyte activation, but the underlying mechanisms are incompletely understood. In this issue of Immunity, Schnyder et al. (2011) and Hashimoto-Tane et al. (2011) show that cytoplasmic dynein drives microcluster centralization along microtubules.
摘要
免疫受体微簇的运动调节淋巴细胞的激活，但潜在的机制尚不完全清楚。在本期《免疫》中，Schnyder 等人（2011）和 Hashimoto-Tane 等人（2011）表明细胞质动力蛋白沿微管驱动微簇的集中化。
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