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膳食因素对中枢神经系统可塑性和损伤恢复的影响。

The influence of dietary factors in central nervous system plasticity and injury recovery.

机构信息

Department of Neurosurgery, University of California Los Angeles Brain Injury Research Center, Los Angeles, CA 90095, USA.

出版信息

PM R. 2011 Jun;3(6 Suppl 1):S111-6. doi: 10.1016/j.pmrj.2011.03.001.

Abstract

Although feeding is an essential component of life, it is only recently that the actions of foods on brain plasticity and function have been scrutinized. There is evidence that select dietary factors are important modifiers of brain plasticity and can have an impact on central nervous system health and disease. Results of new research indicate that dietary factors exert their effects by affecting molecular events related to the management of energy metabolism and synaptic plasticity. Recent study results show that select dietary factors have mechanisms similar to those of exercise, and that, in some cases, dietary factors can complement the action of exercise. Abundant research findings in animal models of central nervous system injury support the idea that nutrients can be taken in through whole foods and dietary supplements to reduce the consequences of neural damage. Therefore, exercise and dietary management appear as a noninvasive and effective strategy to help counteract neurologic and cognitive disorders.

摘要

尽管进食是生命的重要组成部分,但直到最近,食物对大脑可塑性和功能的影响才受到关注。有证据表明,某些饮食因素是大脑可塑性的重要调节剂,会对中枢神经系统的健康和疾病产生影响。新的研究结果表明,饮食因素通过影响与能量代谢和突触可塑性管理相关的分子事件来发挥作用。最近的研究结果表明,某些饮食因素具有类似于运动的机制,在某些情况下,饮食因素可以补充运动的作用。大量中枢神经系统损伤动物模型的研究结果支持这样一种观点,即可以通过全食物和膳食补充剂来摄取营养素,以减轻神经损伤的后果。因此,运动和饮食管理似乎是一种非侵入性且有效的策略,可以帮助对抗神经和认知障碍。

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