Moyano Peregrín Cayetana, López Rodríguez Francisca, Castilla Castellano Maria Del Mar
Servicio de Nefrología, Hospital Costa del Sol, Marbella, Málaga, España.
Med Clin (Barc). 2012 Apr 14;138(9):397-401. doi: 10.1016/j.medcli.2011.04.015. Epub 2011 Jun 23.
Low levels of vitamin D, defined as levels of 25-hydroxyvitamin D < 20-30 ng/ml, is a prevalent problem in the general population. Besides the classic relation with musculoskeletal disease, vitamin D has been also related to autoimmune diseases, cancer, metabolic diseases or cardiovascular diseases. High blood pressure, as the main cardiovascular risk factor, also has been related to vitamin D deficiency, constituting two prevalent worldwide health problems. Therefore, this article reviews the most important studies that combine both pathologies, the biological mechanism that relate them and the current evidence about the effect of vitamin D supplementation on hypertension.
维生素D水平低（定义为25-羟基维生素D水平<20-30 ng/ml）在普通人群中是一个普遍存在的问题。除了与肌肉骨骼疾病的经典关系外，维生素D还与自身免疫性疾病、癌症、代谢性疾病或心血管疾病有关。高血压作为主要的心血管危险因素，也与维生素D缺乏有关，这构成了全球两个普遍存在的健康问题。因此，本文综述了将这两种病症结合起来的最重要研究、将它们联系起来的生物学机制以及目前关于补充维生素D对高血压影响的证据。
