Cardiac Surgery Clinic, Cardiovascular and Thoracic Department, CHU Grenoble, Université Joseph Fourier-Grenoble 1, Grenoble, France.
Can J Cardiol. 2011 Nov-Dec;27(6):685-91. doi: 10.1016/j.cjca.2011.01.014. Epub 2011 Jun 25.
Acute type A aortic dissection (ATAAD) is a life-threatening condition with a poor acute prognosis, which requires rapid and effective surgical management. The aim of this study is to assess our strategy with regard to this condition.
According to a regional emergency protocol, patients with diagnosed or highly suspected ATAAD are directly transferred to the cardiac operating room. Transesophageal echocardiography is performed under anaesthesia, and the patient then undergoes surgery if the diagnosis is confirmed. The present retrospective study examines the implementation of this management strategy between January 1, 1990 and December 31, 2009.
Out of 380 patients, 245 were directly admitted to the operating room. Three hundred twelve cases of ATAAD, 15 cases of aneurysm of the ascending aorta, 9 cases of acute type B dissection, 4 cases of chronic dissection, 4 cases of hemopericardium, and 7 other diagnoses were observed. In 10 cases, no etiology was found. Nineteen patients died before surgery could be performed. Out of the 307 cases of ATAAD undergoing surgery, 15 patients were operated with cardiac massage (14 cases of aortic rupture). This management strategy was justified in 93.1% of patients (228/245) directly admitted to the operating room, because of the need for surgery or aortic rupture.
Our management strategy enabled patients with ATAAD to receive effective and unselective treatment. Despite appropriate management, the large number of patients still dying before surgery, or undergoing surgery with cardiac massage, justifies and consolidates the need for immediate treatment of this condition.
急性A型主动脉夹层(ATAAD)是一种危及生命的疾病,急性预后较差,需要快速有效的手术治疗。本研究旨在评估我们对此种情况的治疗策略。
根据区域性急救方案,诊断或高度怀疑为 ATAAD 的患者将被直接转至心脏手术室。在全身麻醉下进行经食管超声心动图检查,如果确诊,则进行手术。本回顾性研究分析了 1990 年 1 月 1 日至 2009 年 12 月 31 日期间该治疗策略的实施情况。
在 380 例患者中,245 例患者被直接收入手术室。312 例 ATAAD、15 例升主动脉瘤、9 例急性 B 型夹层、4 例慢性夹层、4 例血心包和 7 例其他诊断。在 10 例患者中,未发现病因。19 例患者在手术前死亡。在接受手术的 307 例 ATAAD 患者中,15 例患者行心脏按摩(主动脉破裂 14 例)。由于需要手术或主动脉破裂,245 例直接收入手术室的患者中,93.1%(228/245)采用了这种治疗策略,这种治疗策略是合理的。
我们的治疗策略使 ATAAD 患者能够接受有效且无选择性的治疗。尽管采取了适当的治疗措施,但仍有大量患者在手术前死亡,或在手术中需要行心脏按摩,这一事实证明并加强了对该疾病进行即时治疗的必要性。