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可视化未来:纳米技术增强神经影像学。

Visualizing the future: enhancing neuroimaging with nanotechnology.

机构信息

Department of Neurosurgery, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

出版信息

World Neurosurg. 2011 May-Jun;75(5-6):626-37; discussion 618-9. doi: 10.1016/j.wneu.2011.02.016.

DOI:10.1016/j.wneu.2011.02.016
PMID:21704929
Abstract

Advancements in imaging of the central nervous system have paralleled and propelled neurosurgical practice. These technologic innovations have expanded our understanding of neuroanatomy and neuropathology, helping to refine neurosurgical techniques to be more precise and less invasive. Nanotechnology will play a significant role in the next wave of technology that will continue to improve neurosurgical practice. With specific regard to neuroimaging, nanotechnology has the potential to provide more precise resolution when imaging nervous system malignancies. Nanoparticles may be engineered to noninvasively visualize pathology once found only under a microscope. They will enhance our ability to target new disease processes and thus develop more precise surgical and nonsurgical treatments. This article will discuss the background of nanotechnology's use in imaging of the nervous system, its current status, and future potentials.

摘要

神经系统影像学的进步与神经外科学的发展相辅相成。这些技术创新扩展了我们对神经解剖学和神经病理学的认识,有助于完善神经外科技术,使其更加精确和微创。纳米技术将在推动神经外科学发展的下一波技术浪潮中发挥重要作用。具体到神经影像学,纳米技术有可能提高神经系统恶性肿瘤成像的分辨率。纳米颗粒可以被设计成在显微镜下才能观察到的病理组织的非侵入性可视化。这将增强我们靶向新疾病过程的能力,从而开发更精确的手术和非手术治疗方法。本文将讨论纳米技术在神经系统成像中的应用背景、现状和未来潜力。

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