Sarmah Deepaneeta, Saraf Jackson, Kaur Harpreet, Pravalika Kanta, Tekade Rakesh Kumar, Borah Anupom, Kalia Kiran, Dave Kunjan R, Bhattacharya Pallab
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gandhinagar, Gujarat 382355, India.
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gandhinagar, Gujarat 382355, India.
Micromachines (Basel). 2017 Aug 28;8(9):262. doi: 10.3390/mi8090262.
Stroke is among the leading causes of mortality and morbidity worldwide. Stroke incidences and associated mortality are expected to rise to 23 million and 7.8 million, respectively, by 2030. Further, the aging population, imbalanced lifestyles, and environmental factors continue to shift the rate of stroke incidence, particularly in developing countries. There is an urgent need to develop new therapeutic approaches for treating stroke. Nanotechnology is a growing field, offering an encouraging future prospect for medical research in the management of strokes. The world market for nanotechnology derived products is expected to rise manyfold in the coming decades. Different types of nanomaterials such as perfluorocarbon nanoparticles, iron oxide nanoparticles, gold nanoparticles, polymeric nanoparticles, quantum dots, nanospheres, etc. have been developed for the diagnosis as well as therapy of strokes. Today, nanotechnology has also been integrated with stem cell therapy for treating stroke. However several obstacles remain to be overcome when using such nanomaterials for treating stroke and other neurological diseases.
中风是全球主要的致死和致残原因之一。预计到2030年,中风发病率和相关死亡率将分别上升至2300万和780万。此外,人口老龄化、生活方式不均衡以及环境因素继续改变中风发病率,尤其是在发展中国家。迫切需要开发治疗中风的新疗法。纳米技术是一个不断发展的领域,为中风管理的医学研究提供了令人鼓舞的未来前景。预计在未来几十年,纳米技术衍生产品的全球市场将增长数倍。已开发出不同类型的纳米材料,如全氟化碳纳米颗粒、氧化铁纳米颗粒、金纳米颗粒、聚合物纳米颗粒、量子点、纳米球等,用于中风的诊断和治疗。如今,纳米技术也已与干细胞疗法相结合用于治疗中风。然而,在使用此类纳米材料治疗中风和其他神经疾病时,仍有几个障碍有待克服。