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语言、记忆和言语流畅性改变在颅内动脉瘤性蛛网膜下腔出血患者中的变化:术前研究结果。

Language, memory, and verbal fluency changes in patients with aneurysmal subarachnoid hemorrhage: results of a preoperative investigation.

机构信息

Department of Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, Brazil.

出版信息

World Neurosurg. 2011 May-Jun;75(5-6):653-9; discussion 596-7. doi: 10.1016/j.wneu.2010.10.044.

DOI:10.1016/j.wneu.2010.10.044
PMID:21704932
Abstract

OBJECTIVE

To detect changes in speech, verbal fluency, and memory in patients with subarachnoid hemorrhage (SAH) caused by ruptured aneurysms and to analyze the results before surgical or embolization procedure.

METHODS

During the period May 2007 to November 2009, 193 patients with anterior aneurysmal SAH admitted to the Department of Neurosurgery, Hospital da Restauração, Recife, Brazil, were tested for speech, verbal fluency, and memory disturbances after the first week of bleeding and compared with a control group with similar demographics.

RESULTS

Patients with aneurysmal SAH differed significantly from the control group in language, verbal fluency, and memory functions before clipping or coiling procedures. There were differences in cognitive performance between patients with different aneurysm sites.

CONCLUSIONS

It was possible to characterize the cognitive impairments of each area affected early on in the preoperative period, confirming the assumptions that the aneurysm site could be a determining factor of cognitive impairment.

摘要

目的

检测因破裂动脉瘤引起的蛛网膜下腔出血(SAH)患者的言语、语言流畅性和记忆变化,并分析手术或栓塞术前的结果。

方法

2007 年 5 月至 2009 年 11 月期间,巴西累西腓的 Restauracao 医院神经外科收治了 193 例前交通动脉瘤性 SAH 患者,在出血后第一周检测了他们的言语、语言流畅性和记忆障碍,并与具有相似人口统计学特征的对照组进行了比较。

结果

在夹闭或栓塞前,动脉瘤性 SAH 患者在语言、语言流畅性和记忆功能方面与对照组有显著差异。不同动脉瘤部位的患者认知表现存在差异。

结论

可以在术前早期描述每个受影响区域的认知障碍,证实了动脉瘤部位可能是认知障碍的决定因素的假设。

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引用本文的文献

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Ann Clin Transl Neurol. 2014 Mar;1(3):220-32. doi: 10.1002/acn3.41. Epub 2014 Feb 25.
2
Effect of aneurysmal subarachnoid hemorrhage on word generation.动脉瘤性蛛网膜下腔出血对词语生成的影响。
Behav Neurol. 2014;2014:610868. doi: 10.1155/2014/610868. Epub 2014 Mar 2.
3
The importance of early brain injury after subarachnoid hemorrhage.蛛网膜下腔出血后早期脑损伤的重要性。
Prog Neurobiol. 2012 Apr;97(1):14-37. doi: 10.1016/j.pneurobio.2012.02.003. Epub 2012 Mar 10.