Kumar Suresh, Kamboj Jitpal, Sharma Sunil
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, India.
J Acupunct Meridian Stud. 2011 Jun;4(2):134-40. doi: 10.1016/S2005-2901(11)60020-4.
Herbal remedies have become popular, due in part to the lower risk of adverse reactions. Thousands of plants have been used traditionally to treat various diseases. Among them, species of the genus Piper are important medicinal plants used in various systems of medicine. The Piper longum fruit has been used in traditional medicine, including the Ayurvedic system of medicine. Although there are numerous indications for its use, controlled trials are needed to determine its efficacy. The primary constituents isolated from various parts of P. longum are piperine, piperlongumine, sylvatin, sesamin, diaeudesmin piperlonguminine, pipermonaline, and piperundecalidine. It is most commonly used to treat chronic bronchitis, asthma, constipation, gonorrhea, paralysis of the tongue, diarrhea, cholera, chronic malaria, viral hepatitis, respiratory infections, stomachache, bronchitis, diseases of the spleen, cough, and tumors. This study provides detailed information about the P. longum fruit, including phytochemistry, pharmacological profile and safety profile. In view of the commercial, economic, and medicinal importance of the P. longum plant, it is useful for researchers to study the plant in detail.
草药疗法已变得流行，部分原因是不良反应风险较低。数千种植物传统上被用于治疗各种疾病。其中，胡椒属植物是在各种医学体系中使用的重要药用植物。荜茇果实已用于传统医学，包括阿育吠陀医学体系。尽管其使用有众多适应症，但仍需要对照试验来确定其疗效。从荜茇的各个部位分离出的主要成分有胡椒碱、荜茇宁、西维亭、芝麻素、二氢荜茇明、胡椒莫林碱和胡椒十一碳碱。它最常用于治疗慢性支气管炎、哮喘、便秘、淋病、舌麻痹、腹泻、霍乱、慢性疟疾、病毒性肝炎、呼吸道感染、胃痛、支气管炎、脾脏疾病、咳嗽和肿瘤。本研究提供了关于荜茇果实的详细信息，包括植物化学、药理学特征和安全性概况。鉴于荜茇植物的商业、经济和药用重要性，研究人员对该植物进行详细研究是有用的。
