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痤疮丙酸杆菌 IB 型菌株 6609 的全基因组序列。

Complete genome sequence of Propionibacterium acnes type IB strain 6609.

机构信息

Institute for Plant Genomics, Human Biotechnology and Bioenergy, Bay Zoltán Foundation for Applied Research, Pf 1281, 6726 Szeged, Hungary.

出版信息

J Bacteriol. 2011 Sep;193(17):4561-2. doi: 10.1128/JB.05372-11. Epub 2011 Jun 24.

DOI:10.1128/JB.05372-11
PMID:21705602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3165515/
Abstract

Propionibacterium acnes is an anaerobic Gram-positive bacterium that forms part of the normal human cutaneous microbiota and is thought to play a central role in acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit (I. Kurokawa et al., Exp. Dermatol. 18:821-832, 2009). Here we present the whole genome sequence of P. acnes type IB strain 6609, which was recovered from a skin sample from a woman with no recorded acne history and is thus considered a nonpathogenic strain (I. Nagy, Microbes Infect. 8:2195-2205, 2006).

摘要

痤疮丙酸杆菌是一种厌氧革兰氏阳性细菌,是正常人体皮肤微生物群的一部分,被认为在寻常痤疮中起核心作用,寻常痤疮是一种毛囊皮脂腺单位的慢性炎症性疾病(I. Kurokawa 等人,Exp. Dermatol. 18:821-832,2009)。本文呈现了从一位无痤疮病史女性的皮肤样本中分离出的、被认为是非致病菌的痤疮丙酸杆菌 IB 型 6609 株的全基因组序列(I. Nagy,Microbes Infect. 8:2195-2205,2006)。

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本文引用的文献

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A novel multilocus sequence typing scheme for the opportunistic pathogen Propionibacterium acnes and characterization of type I cell surface-associated antigens.一种用于机会性病原体痤疮丙酸杆菌的新型多位点序列分型方案和 I 型细胞表面相关抗原的特征。
Microbiology (Reading). 2011 Jul;157(Pt 7):1990-2003. doi: 10.1099/mic.0.049676-0. Epub 2011 Apr 21.
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Population genetic analysis of Propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne.痤疮丙酸杆菌的群体遗传学分析鉴定出与痤疮相关的亚群和流行克隆。
PLoS One. 2010 Aug 19;5(8):e12277. doi: 10.1371/journal.pone.0012277.
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New developments in our understanding of acne pathogenesis and treatment.我们对痤疮发病机制及治疗的新进展。
Exp Dermatol. 2009 Oct;18(10):821-32. doi: 10.1111/j.1600-0625.2009.00890.x. Epub 2009 Jun 23.
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A new phylogenetic group of Propionibacterium acnes.痤疮丙酸杆菌的一个新系统发育群。
J Med Microbiol. 2008 Feb;57(Pt 2):218-224. doi: 10.1099/jmm.0.47489-0.
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Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes.痤疮丙酸杆菌和脂多糖可诱导人皮脂腺细胞中抗菌肽和促炎细胞因子/趋化因子的表达。
Microbes Infect. 2006 Jul;8(8):2195-205. doi: 10.1016/j.micinf.2006.04.001. Epub 2006 May 19.
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