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颈椎终板和小关节骨关节炎:尸体标本的解剖学研究

Cervical endplate and facet arthrosis: an anatomic study of cadaveric specimens.

作者信息

Master Daniel L, Toy Jason O, Eubanks Jason D, Ahn Nicholas U

机构信息

Department of Orthopaedic Surgery, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

出版信息

J Spinal Disord Tech. 2012 Oct;25(7):379-82. doi: 10.1097/BSD.0b013e318224a60f.

DOI:10.1097/BSD.0b013e318224a60f
PMID:21705919
Abstract

STUDY DESIGN

An anatomic, epidemiologic study of cervical endplate and facet arthrosis in cadaveric spines.

OBJECTIVE

To determine the prevalence of cervical endplate and facet arthrosis and the relationship between these 2 entities in a large population sample.

SUMMARY OF BACKGROUND DATA

Cervical endplate and facet arthrosis are common radiographic findings, which have both been linked to pain. However, the prevalence and relationship between cervical endplate and facet arthrosis has not been clearly defined.

METHODS

The cervical vertebrae from 234 cadaveric spines were examined by a single investigator for evidence of endplate and facet arthrosis. Arthrosis at each endplate and facet was graded on a continuum from 0 to IV. Race, age at death, and sex of each specimen were also recorded. Stepwise multiple linear regression was used to analyze any association between race, age, sex, endplate arthrosis, and facet arthrosis. Factors with P values <0.05 remained in the analysis. Two-tailed t tests for matched samples were used to analyze any difference between mean endplate and facet arthrosis severity scores among patients within the same decades of life.

RESULTS

Concurrent cervical endplate and facet arthrosis was present in 77% of the study population. Stepwise multiple linear regression revealed significant (P<0.01) associations between endplate and facet arthrosis and between age and facet arthrosis. Race and sex did not correlate with facet arthrosis. In addition, patients in age groups 30 to 39, 40 to 49, 50 to 59, 60 to 69, 70 to 79, and 80 to 89 demonstrated more severe (P<0.01) endplate arthrosis in comparison with facet arthrosis.

CONCLUSIONS

Concurrent cervical endplate and facet arthrosis is a common condition. Cervical endplate arthrosis and advancing age are associated with cervical facet arthrosis independent of race and sex. Cervical endplate arthrosis precedes facet arthrosis.

摘要

研究设计

对尸体颈椎的终板和小关节骨关节炎进行解剖学、流行病学研究。

目的

确定颈椎终板和小关节骨关节炎的患病率以及在大量人群样本中这两种情况之间的关系。

背景数据总结

颈椎终板和小关节骨关节炎是常见的影像学表现,两者均与疼痛有关。然而,颈椎终板和小关节骨关节炎之间的患病率及关系尚未明确界定。

方法

由一名研究人员对234具尸体颈椎进行检查,以寻找终板和小关节骨关节炎的证据。每个终板和小关节的骨关节炎按0至IV级连续分级。记录每个标本的种族、死亡年龄和性别。采用逐步多元线性回归分析种族、年龄、性别、终板骨关节炎和小关节骨关节炎之间的任何关联。P值<0.05的因素保留在分析中。使用配对样本的双尾t检验分析同一十年年龄段患者的平均终板和小关节骨关节炎严重程度评分之间的任何差异。

结果

77%的研究人群同时存在颈椎终板和小关节骨关节炎。逐步多元线性回归显示终板和小关节骨关节炎之间以及年龄和小关节骨关节炎之间存在显著(P<0.01)关联。种族和性别与小关节骨关节炎无关。此外,与小关节骨关节炎相比,年龄在30至39岁、40至49岁、50至59岁、60至69岁、70至79岁和80至89岁的患者终板骨关节炎更严重(P<0.01)。

结论

颈椎终板和小关节骨关节炎同时存在是一种常见情况。颈椎终板骨关节炎和年龄增长与颈椎小关节骨关节炎相关,与种族和性别无关。颈椎终板骨关节炎先于小关节骨关节炎出现。

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