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[卡介苗接种后结核感染的检测]

[Detection of tubercular infection after BCG vaccination].

作者信息

Rogoz I

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1978 Oct-Dec;27(4):217-21.

PMID:217060
Abstract

The author has followed several groups of children over a period of many years and evidenced the general decrease of the level of tuberculin reactivity. The implications are discussed, of the B.C.G. vaccination on the tuberculous allergy and the possibility to differentiate post-vaccinal allergy with the aid of skin testing, using 2 and 10 PPD units. The importance is stressed, of the vaccinal scar as an indication of a good immune reactivity, and thus of protection against contamination with virulent tuberculous baccili. The time is foreseen, when systematic vaccination with B.C.G. will reduce to such a significant degree the number of cases of tuberculosis in children that differential diagnosis on the basis of tuberculin allergy will not be necessary.

摘要

作者对几组儿童进行了多年跟踪,证实结核菌素反应水平普遍下降。文中讨论了卡介苗接种对结核过敏的影响,以及借助皮肤试验(使用2个和10个结核菌素单位)区分接种后过敏的可能性。强调了接种疤痕作为良好免疫反应的指标的重要性,从而作为预防感染毒性结核杆菌的指标。预计在未来,卡介苗的系统接种将大幅减少儿童结核病病例数量,以至于无需根据结核菌素过敏进行鉴别诊断。

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