Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Matern Child Health J. 2012 Jul;16(5):1120-30. doi: 10.1007/s10995-011-0840-7.
Recently, federal funding was designated through the Patient Protection and Affordable Care Act giving states the opportunity to expand their prenatal case management programs (PCM) through home visitation. Studies evaluating the effect of PCM on birth outcomes have shown little or no positive results. One suggested reason for these findings is a lack of attention in the assessment of dosage. The objective of this study is to demonstrate the use of measuring PCM dosage when assessing pregnancy outcomes. A birth cohort (N = 4,582) encompassing Medicaid-insured Iowa residents enrolled in PCM who gave birth to a singleton from October 2005 to December 2006 was constructed from linked Iowa birth, Medicaid Claims, and Women's Health Information Systems datasets. Data was used to create a dosage measure capturing the duration of enrollment, amount of time spent with a case manager, and breadth of interventions. Bivariate analysis and logistic regression were used to assess the relationship between PCM dosage and the birth outcomes. Dosage was significantly associated with LBW (X (2) = 31.1, P < 0.001) and PTB (X (2) = 56.2, P < 0.001). After adjustment for potential confounders, the likelihood of LBW and PTB were aOR: 0.47 (95% CI: 0.36-0.63) and aOR: 0.60 (95% CI: 0.44-0.82) for women with medium dosage (compared to low dosage), respectively. For women with high PCM dosage the likelihood of LBW and PTB was aOR 0.40 (95% CI: 0.31-0.51) and aOR = 0.62 (95% CI: 0.48-0.81), respectively. This study showed that PCM dosage was significantly associated with lower odds of an adverse pregnancy outcome occurring.
最近,根据《患者保护与平价医疗法案》,联邦资金被指定用于使各州能够通过家访扩大其产前病例管理计划(PCM)。评估 PCM 对生育结果影响的研究表明,效果甚微或没有积极效果。造成这些发现的一个原因是在评估剂量时缺乏关注。本研究旨在展示在评估妊娠结果时使用 PCM 剂量测量。构建了一个包含 Medicaid 保险的爱荷华州居民的出生队列(N = 4582),这些居民参加了 PCM,并于 2005 年 10 月至 2006 年 12 月期间生下了一个单胎。数据来自爱荷华州出生、医疗补助索赔和妇女健康信息系统数据集的链接。数据用于创建一个剂量测量值,该测量值捕获了登记的持续时间、与病例经理相处的时间以及干预措施的广度。使用双变量分析和逻辑回归来评估 PCM 剂量与生育结果之间的关系。剂量与 LBW(X (2) = 31.1,P < 0.001)和 PTB(X (2) = 56.2,P < 0.001)显著相关。在调整了潜在的混杂因素后,中剂量(与低剂量相比)的 LBW 和 PTB 的可能性分别为 aOR:0.47(95%CI:0.36-0.63)和 aOR:0.60(95%CI:0.44-0.82)。对于高剂量 PCM 的女性,LBW 和 PTB 的可能性分别为 aOR 0.40(95%CI:0.31-0.51)和 aOR = 0.62(95%CI:0.48-0.81)。本研究表明,PCM 剂量与不良妊娠结局的发生几率呈显著负相关。