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评估对改良戒烟药物的偏好:一项离散选择实验。

Assessing preferences for improved smoking cessation medications: a discrete choice experiment.

机构信息

Faculty of Economics, Institute for Research in Economics, University of Neuchâtel, 2000, Neuchâtel, Switzerland.

出版信息

Eur J Health Econ. 2012 Oct;13(5):533-48. doi: 10.1007/s10198-011-0333-z. Epub 2011 Jun 26.

Abstract

BACKGROUND

The use of smoking cessation medications can considerably enhance the long-term abstinence rate at a reasonable cost, but only a small proportion of quitters seek medical assistance. The objective of this study was to evaluate the factors that influence the decision to use such treatments and the willingness-to-pay of smokers for improved cessation drugs.

METHOD

A discrete choice experiment was conducted amongst smokers in the French-speaking part of Switzerland. Choice sets consisted of two hypothetical medications described via five attributes (price, efficacy, possibility of minor side effects, attenuation of weight gain and availability) and an opt-out option. Various discrete choice models were estimated to analyse both the factors that influence treatment choice and those that influence the overall propensity to use a smoking cessation medication.

RESULTS

Our results indicate that smokers are willing to pay for higher efficacy, less-frequent side effects and prevention of weight gain. Whether the drug is available over-the-counter or on medical prescription is of secondary importance. In addition, we show that there are several individual-specific factors influencing the decision to use such medications, including education level. Results also indicate substantial preference heterogeneity.

CONCLUSION

This study shows that there is a potential demand for improved cessation medications. Broader usage could be reached through lower out-of-pocket price and greater efficacy. Secondary aspects such as side effects and weight gain should also be taken into consideration.

摘要

背景

使用戒烟药物可以在合理的成本下显著提高长期戒烟率,但只有一小部分戒烟者寻求医疗帮助。本研究旨在评估影响使用这些治疗方法的决策的因素以及吸烟者对改善戒烟药物的支付意愿。

方法

在瑞士法语区的吸烟者中进行了一项离散选择实验。选择集由两种假设的药物组成,通过五个属性(价格、疗效、轻微副作用的可能性、体重增加的减轻和可用性)和一个退出选项来描述。估计了各种离散选择模型,以分析影响治疗选择的因素以及影响整体使用戒烟药物倾向的因素。

结果

我们的结果表明,吸烟者愿意为更高的疗效、更频繁的副作用和预防体重增加支付更高的费用。药物是否可以在柜台或凭处方购买是次要的。此外,我们还表明,有几个个体特定的因素会影响使用这些药物的决策,包括教育水平。结果还表明存在大量的偏好异质性。

结论

本研究表明,人们对改善戒烟药物有潜在的需求。通过降低自付费用和提高疗效,可以实现更广泛的使用。还应考虑次要方面,如副作用和体重增加。

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