Terzic Andre, Edwards Brooks S, McKee Katherine C, Nelson Timothy J
Mayo Clinic Center for Regenerative Medicine, USA.
Minn Med. 2011 May;94(5):44-7.
Regenerative medicine aims to restore homeostasis through a broad spectrum of strategies ranging from transplantation of donor organs to augmentation of innate healing processes. Its first clinical application emerged five decades ago when bone marrow-derived stem cells were used to replace defective progenitor cells. Since then, a variety of technological advances have expanded its scope. Most recently, the advent of natural or bioengineered stem cell products for tissue repair has inspired hope that the toughest obstacles in transplant medicine--the shortage of organs and organ rejection--might be overcome.This article describes the evolution of regenerative medicine and some of the ways it is being used in research and clinical practice.
再生医学旨在通过一系列广泛的策略恢复体内平衡，这些策略涵盖从供体器官移植到增强固有愈合过程等各个方面。其首次临床应用出现在五十年前，当时骨髓来源的干细胞被用于替代有缺陷的祖细胞。从那时起，各种技术进步扩大了其范围。最近，用于组织修复的天然或生物工程干细胞产品的出现激发了人们的希望，即移植医学中最棘手的障碍——器官短缺和器官排斥反应——可能会被克服。本文描述了再生医学的发展历程以及它在研究和临床实践中的一些应用方式。
