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评估联合胎儿头皮血采样中 pH 值与乳酸值之间的差异。

Evaluation of the discrepancy between pH and lactate in combined fetal scalp blood sampling.

机构信息

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

出版信息

Acta Obstet Gynecol Scand. 2011 Oct;90(10):1088-93. doi: 10.1111/j.1600-0412.2011.01228.x. Epub 2011 Jul 27.

DOI:10.1111/j.1600-0412.2011.01228.x
PMID:21707554
Abstract

OBJECTIVE

To evaluate the rate of discrepancy between pH and lactate values in fetal blood sampling (FBS). To evaluate differences in obstetric management in response to combined tests (pH and lactate) and single tests (pH or lactate).

DESIGN

Descriptive study.

SETTING

Uppsala University Hospital, Sweden.

POPULATION

Labors monitored by FBS during one year (n=241).

METHODS

Discrepancy in the combined tests was defined as a test having one abnormal and one normal value. Abnormal pH was defined as 7.24 or lower and abnormal lactate as 4.2 or higher. The results were categorized according to whether the test was normal or abnormal and according to whether it was a combined or single analysis.

MAIN OUTCOME MEASURES

Discrepancy between pH and lactate values in combined tests. Frequency of operative delivery for fetal distress (ODFD). Time interval from the last FBS to ODFD.

RESULTS

In the combined tests with abnormality, a discrepancy between pH and lactate values occurred in 55%. The mean time interval from the last FBS to ODFD was longer in combined tests with one abnormal compared with two abnormal test results, 75 vs. 37 minutes (p<0.05). Operative delivery for fetal distress was performed less often after combined tests than after single tests: 41/62 (66%) vs. 19/20 (95%) (p<0.05).

CONCLUSION

In the combined test, discrepancies were common and occurred in half of the samples with an abnormality. Obstetric management was influenced by the discrepancy between test results with respect to ODFD rates and the time interval from the last FBS to delivery.

摘要

目的

评估胎儿血样采集(FBS)中 pH 值和乳酸值之间差异的发生率。评估联合检测(pH 值和乳酸值)和单项检测(pH 值或乳酸值)对产科处理的影响。

设计

描述性研究。

地点

瑞典乌普萨拉大学医院。

人群

一年内通过 FBS 监测的分娩(n=241)。

方法

联合检测中异常的定义为一项检测结果异常,另一项检测结果正常。异常 pH 值定义为 7.24 或更低,异常乳酸值定义为 4.2 或更高。结果根据检测结果是否正常以及是联合分析还是单项分析进行分类。

主要观察指标

联合检测中 pH 值和乳酸值之间的差异。因胎儿窘迫行剖宫产术(ODFD)的频率。从最后一次 FBS 到 ODFD 的时间间隔。

结果

在异常的联合检测中,pH 值和乳酸值之间存在差异的情况占 55%。与两项异常检测结果相比,最后一次 FBS 到 ODFD 的时间间隔在一项异常的联合检测中更长,分别为 75 分钟和 37 分钟(p<0.05)。与单项检测相比,联合检测后行 ODFD 的剖宫产术更少:41/62(66%)与 19/20(95%)(p<0.05)。

结论

在联合检测中,差异很常见,在一半有异常的样本中出现。对于 ODFD 发生率和从最后一次 FBS 到分娩的时间间隔,检测结果之间的差异会影响产科处理。

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